Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm

Stable Identifier
Reaction [transition]
Homo sapiens
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During interphase, cyclin B1 shuttles continuously in and out of the nucleus. The cyclin B cytoplasmic retention sequence (CRS), which is responsible for its interphase cytoplasmic localization, functions as a nuclear export sequence (Yang et al., 1998).

Literature References
PubMed ID Title Journal Year
9670027 MPF localization is controlled by nuclear export

Pines, J, Hagting, A, Clute, P, Karlsson, C, Jackman, M

EMBO J 1998
9679058 Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1

Kornbluth, S, Powers, MA, Yang, J, Moore, JD, Brennan, J, Bardes, ES

Genes Dev 1998
This event is regulated
Positively by
Orthologous Events
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