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Reducing equivalents from beta-oxidation of fatty acids transfer to ETF
Stable Identifier
R-HSA-169260
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Homo sapiens)
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Electron transfer flavoprotein (ETF) is a 63kDa heterodimer composed of alpha and beta subunits and binds one FAD and one AMP per dimer. ETF resides on the matrix face of the mitochondrial inner membrane. Reducing equivalents from the beta-oxidation of fatty acyl CoAs are transferred to ETF, reducing the ETF-bound FAD to FADH2 (Wood 1999).
Literature References
PubMed ID
Title
Journal
Year
10327278
Defects in mitochondrial beta-oxidation of fatty acids
Wood, PA
Curr. Opin. Lipidol.
1999
Participants
Input
ETF:FAD [mitochondrial matrix]
(Homo sapiens)
FADH2 [mitochondrial matrix]
Output
ETF:FADH2 [mitochondrial matrix]
(Homo sapiens)
FAD [mitochondrial matrix]
Participates
as an event of
Respiratory electron transport (Homo sapiens)
Catalyst Activity
electron transfer activity of ETF:FAD [mitochondrial matrix]
Physical Entity
ETF:FAD [mitochondrial matrix]
(Homo sapiens)
Activity
electron transfer activity (GO:0009055)
Orthologous Events
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Caenorhabditis elegans)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Canis familiaris)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Danio rerio)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Dictyostelium discoideum)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Drosophila melanogaster)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Mus musculus)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Rattus norvegicus)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Saccharomyces cerevisiae)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Schizosaccharomyces pombe)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Sus scrofa)
Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Xenopus tropicalis)
Created
Jassal, B (2005-11-25)
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