Binding of NEP/NS2 to vRNP:M1

Stable Identifier
R-HSA-168893
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Binding of NEP/NS2 to vRNP:M1
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Structural characterization of NEP/NS2 suggests that acidic residues in the C-terminus of NEP/NS2 bind to M1, with Trp78 critical for interaction (Ward, 1995; Yasuda, 1993; Akarsu, 2003).
Literature References
PubMed ID Title Journal Year
7503702 Expression and analysis of the NS2 protein of influenza A virus

Ward, AC, Castelli, LA, Lucantoni, AC, White, JF, Azad, AA, Macreadie, IG

Arch Virol 1995
8356796 Molecular assembly of influenza virus: association of the NS2 protein with virion matrix

Yasuda, J, Nakada, S, Kato, A, Toyoda, T, Ishihama, A

Virology 1993
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
intracellular transport of virus (0075733)
Disease
Name Identifier Synonyms
influenza DOID:8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Cross References
Mondo
Authored
Bortz, E  (2007-02-13)
Garcia-Sastre, A  (2007-02-13)
Reviewed
Squires, B  (2007-02-13)
Created
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