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Association of NP into rafts
Stable Identifier
R-HSA-168882
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
Golgi membrane
ReviewStatus
5/5
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Virus Assembly and Release (Homo sapiens)
Assembly of Viral Components at the Budding Site (Homo sapiens)
Association of NP into rafts (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
There is evidence that NP alone is intrinsically targeted to the apical plasma membrane and associates with lipid rafts in a cholesterol-dependent manner, which suggests that RNPs could reach the assembly site independently of the other viral components.
Literature References
PubMed ID
Title
Journal
Year
15522099
Lipid raft-dependent targeting of the influenza A virus nucleoprotein to the apical plasma membrane
Amorim, MJ
,
Digard, P
,
Carrasco, M
Traffic
2004
Participants
Input
Lipid Raft [Golgi membrane]
NP [Golgi membrane]
(Influenza A virus)
Output
NP:Lipid Raft [Golgi membrane]
(Influenza A virus)
Participates
as an event of
Assembly of Viral Components at the Budding Site (Homo sapiens)
Event Information
Go Biological Process
virion assembly (0019068)
Disease
Name
Identifier
Synonyms
influenza
DOID:8469
Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Authored
Steel, J (2007-05-01)
Reviewed
Squires, B (2007-05-01)
Rush, MG (2007-05-01)
Created
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