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SREBP1A,1C,2:SCAP translocates to the Golgi
Stable Identifier
R-HSA-1655834
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
,
ER to Golgi transport vesicle membrane
,
Golgi membrane
Synonyms
SREBF1A,1C,2:SCAP translocates to the Golgi
ReviewStatus
5/5
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Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
SREBP1A,1C,2:SCAP translocates to the Golgi (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
In low concentrations of cholesterol SCAP interacts with Sec24 of the CopII coat complex causing SCAP:SREBP1A/1C/2 to be transported with the CopII complex from the endoplasmic reticulum to the Golgi.
Participants
Input
SREBP1A,1C,2:SCAP:Cop II Coat [endoplasmic reticulum membrane]
(Homo sapiens)
Output
SREBP1A,1C,2:SCAP [Golgi membrane]
(Homo sapiens)
Participates
as an event of
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
Inferred From
SREBP2:SCAP Transits to the Golgi (Cricetulus griseus)
Authored
May, B (2011-09-28)
Reviewed
Liang, G (2012-08-26)
Created
May, B (2011-10-13)
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