Expression of Lanosterol Synthase (LSS)

Stable Identifier
R-HSA-1655828
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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The LSS gene is transcribed to yield mRNA and the mRNA is translated to yield protein.

Literature References
PubMed ID Title Journal Year
17925399 Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression

Villagra, A, Ulloa, N, Zhang, X, Yuan, Z, Sotomayor, E, Seto, E

J Biol Chem 2007
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Summation

SREBF1A (SREBP1A) and SREBF2 (SREBP2) bind the promoter of the Lanosterol Synthase (LSS) gene and enhance transcription (Pai et al. 1998, Sakakura et al. 2001, Reed et al. 2008, reviewed in Horton et al. 2002).

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