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SCAP [Golgi membrane]
Stable Identifier
R-HSA-1655739
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Sterol regulatory element-binding protein cleavage-activating protein, SCAP_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
S1P hydrolyzes SREBP1A,1C,2 (Homo sapiens)
SCAP tetramer [Golgi membrane] (Homo sapiens)
SCAP [Golgi membrane] (Homo sapiens)
SREBP1A,1C,2:SCAP [Golgi membrane] (Homo sapiens)
SCAP tetramer [Golgi membrane] (Homo sapiens)
SCAP [Golgi membrane] (Homo sapiens)
SREBP1A,1C,2:SCAP translocates to the Golgi (Homo sapiens)
SREBP1A,1C,2:SCAP [Golgi membrane] (Homo sapiens)
SCAP tetramer [Golgi membrane] (Homo sapiens)
SCAP [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12770 SCAP
Gene Names
SCAP, KIAA0199, PSEC0227
Chain
chain:1-1279
Reference Genes
BioGPS Gene:22937 SCAP
COSMIC (genes):SCAP SCAP
CTD Gene:22937 SCAP
dbSNP Gene:22937 SCAP
ENSEMBL:ENSG00000114650 SCAP
HGNC:30634 SCAP
Monarch:22937 SCAP
NCBI Gene:22937 SCAP
OMIM:601510 SCAP
UCSC:Q12770 SCAP
Reference Transcript
RefSeq:NM_012235.3 SCAP
RefSeq:XM_017005921.1 SCAP
RefSeq:XM_017005918.1 SCAP
RefSeq:XM_011533501.1 SCAP
Other Identifiers
11717586_a_at
11744812_x_at
16953123
212329_PM_at
212329_at
22937
2672713
2672714
2672715
2672716
2672717
2672718
2672719
2672720
2672722
2672723
2672724
2672727
2672728
2672729
2672730
2672731
2672732
2672734
2672735
2672736
2672737
2672738
2672739
2672740
2672741
2672742
2672743
2672744
2672745
2672746
2672747
2672748
2672750
2672751
2672752
2672753
2672754
2672755
2672756
2672757
2672758
2672759
2672760
2672761
2672762
2672763
2672766
2672767
37656_at
63096_at
8086754
A_23_P252825
D83782_at
GE57341
GO:0000139
GO:0001666
GO:0002376
GO:0005515
GO:0005783
GO:0005789
GO:0005794
GO:0006629
GO:0006955
GO:0008203
GO:0008289
GO:0012507
GO:0016020
GO:0019217
GO:0031410
GO:0032868
GO:0032933
GO:0032934
GO:0032936
GO:0032991
GO:0033552
GO:0042304
GO:0043226
GO:0044255
GO:0044877
GO:0045540
GO:0045541
GO:0045542
GO:0051082
GO:0090110
HMNXSV003039183
Hs.78442.0.S1_3p_at
ILMN_1677534
PH_hs_0020641
TC03001367.hg
TC03002894.hg
Participates
as a component of
SCAP tetramer [Golgi membrane] (Homo sapiens)
Other forms of this molecule
SCAP [endoplasmic reticulum membrane]
Inferred To
Scap [Golgi membrane]
(Mus musculus)
Scap [Golgi membrane]
(Rattus norvegicus)
scap [Golgi membrane]
(Xenopus tropicalis)
SCAP [Golgi membrane]
(Bos taurus)
SCAP [Golgi membrane]
(Canis familiaris)
SCAP [Golgi membrane]
(Drosophila melanogaster)
SCAP [Golgi membrane]
(Gallus gallus)
SCAP [Golgi membrane]
(Sus scrofa)
scp-1 [Golgi membrane]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENSP00000265565
,
ENST00000648151
,
ENSP00000497087
,
ENST00000265565
OpenTargets
ENSG00000114650
HPA
ENSG00000114650-SCAP
PRO
Q12770
Pharos - Targets
Q12770
GlyGen
Q12770
HMDB Protein
HMDBP08576
PDB
7ETW
,
6M49
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H8X2 IPPK
2
IPPK [cytosol]
(R-HSA-1604598)
IPPK [nucleoplasm]
(R-HSA-2023949)
0.527
2
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