mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate

Stable Identifier
R-HSA-162821
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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In the eighth reaction of GPI synthesis, a third mannose residue is added, catalyzed by PIG-B (Takahashi et al. 1996).

Literature References
PubMed ID Title Journal Year
8861954 PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor

Takahashi, M, Inoue, N, Ohishi, K, Maeda, Y, Nakamura, N, Endo, Y, Fujita, T, Takeda, J, Kinoshita, T

EMBO J 1996
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
glycolipid mannosyltransferase activity of PIGB [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored
Created
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