Reactome | CTRB2(167-263) [extracellular region]

CTRB2(167-263) [extracellular region]

Stable Identifier

R-HSA-1604686

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

CTRB2C, Chymotrypsin B2 chain C, CTRB2_HUMAN, CTRB2

Locations in the PathwayBrowser

Expand all

Extracellular matrix organization (Homo sapiens)

- Degradation of the extracellular matrix (Homo sapiens)
  - Activation of Matrix Metalloproteinases (Homo sapiens)
    - Activation of proMMP10 (Homo sapiens)
      - proMMP10 activators [extracellular region] (Homo sapiens)
        
        CTRB2 [extracellular region] (Homo sapiens)
        
        CTRB2(167-263) [extracellular region] (Homo sapiens)

Metabolism (Homo sapiens)

- Metabolism of vitamins and cofactors (Homo sapiens)
  - Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
    - Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
      - Uptake of dietary cobalamins into enterocytes (Homo sapiens)
        
        Pancreatic proteases degrade TCN1:RCbl (Homo sapiens)
        
        PRSS1,3,CTRB1,2 [extracellular region] (Homo sapiens)
        
        CTRB2 [extracellular region] (Homo sapiens)
        
        CTRB2(167-263) [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q6GPI1 CTRB2

Gene Names

CTRB2

Chain

signal peptide:1-18, chain:19-263, chain:19-31, chain:34-164, chain:167-263

Reference Genes

BioGPS Gene:440387 CTRB2

COSMIC (genes):CTRB2 CTRB2

CTD Gene:440387 CTRB2

dbSNP Gene:440387 CTRB2

ENSEMBL:ENSG00000168928.13 CTRB2

HGNC:2522 CTRB2

KEGG Gene (Homo sapiens):440387 CTRB2

Monarch:440387 CTRB2

NCBI Gene:440387 CTRB2

OMIM:619620 CTRB2

UCSC:Q6GPI1 CTRB2

Reference Transcript

RefSeq:NM_001025200.3 CTRB2

Other Identifiers

11715688_x_at

11757286_s_at

205971_PM_s_at

205971_s_at

214411_3p_x_at

214411_PM_x_at

214411_x_at

36141_at

3668925

3668926

3668927

3668929

3668931

3668932

3668935

3668941

3699391

3699392

3699394

3699399

3699401

3699403

3699404

3699409

440387

7997264

8002845

A_23_P431139

A_32_P86150

GO:0003824

GO:0004252

GO:0005576

GO:0005615

GO:0006508

GO:0007586

GO:0008233

GO:0008236

GO:0016787

GO:0140096

HMNXSV003050947

Hs.74502.1.S1_3p_a_at

Hs.74502.1.S1_3p_x_at

ILMN_1651430

ILMN_1767643

ILMN_2137654

M24400_at

TC16000617.hg

TC16001275.hg

g4503134_3p_a_at

Participates

as a component of

CTRB2 [extracellular region] (Homo sapiens)

Other forms of this molecule

CTRB2(34-164) [extracellular region]

CTRB2(19-31) [extracellular region]

Inferred To

Ctrb1 [extracellular region] (Mus musculus)

Ctrb1 [extracellular region] (Rattus norvegicus)

LOC121106428 [extracellular region] (Gallus gallus)

anon-WO0140519.112 [extracellular region] (Drosophila melanogaster)

Homologues of CTRB1(167-263) [extracellular region] (Gallus gallus)

CTRB1(167-263) [extracellular region] (Danio rerio)

CTRB1(167-263) [extracellular region] (Gallus gallus)

CTRB1(167-263) [extracellular region] (Sus scrofa)

CTRB1 [extracellular region] (Bos taurus)

CTRB1 [extracellular region] (Canis familiaris)

Ghost homologue of CTRB2(167-263) [extracellular region] (Xenopus tropicalis)

Cross References

RefSeq

NP_001020371.3

OpenTargets

ENSG00000168928

HPA

ENSG00000168928-CTRB2

GeneCards

Q6GPI1

Ensembl

ENST00000303037, ENSP00000303963, ENSG00000168928

PRO

Q6GPI1

Pharos - Targets

Q6GPI1