Reactome | CTRB2(167-263) [extracellular region]

CTRB2(167-263) [extracellular region]

Stable Identifier

R-HSA-1604686

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

CTRB2C, Chymotrypsin B2 chain C, CTRB2_HUMAN, CTRB2

Locations in the PathwayBrowser

Expand all

Extracellular matrix organization (Homo sapiens)

- Degradation of the extracellular matrix (Homo sapiens)
  - Activation of Matrix Metalloproteinases (Homo sapiens)
    - Activation of proMMP10 (Homo sapiens)
      - proMMP10 activators [extracellular region] (Homo sapiens)
        
        CTRB2 [extracellular region] (Homo sapiens)
        
        CTRB2(167-263) [extracellular region] (Homo sapiens)

Metabolism (Homo sapiens)

- Metabolism of vitamins and cofactors (Homo sapiens)
  - Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
    - Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
      - Uptake of dietary cobalamins into enterocytes (Homo sapiens)
        
        Pancreatic proteases degrade TCN1:RCbl (Homo sapiens)
        
        PRSS1,3,CTRB1,2 [extracellular region] (Homo sapiens)
        
        CTRB2 [extracellular region] (Homo sapiens)
        
        CTRB2(167-263) [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q6GPI1 CTRB2

Gene Names

CTRB2

Chain

signal peptide:1-18, chain:19-263, chain:19-31, chain:34-164, chain:167-263

Reference Genes

BioGPS Gene:440387 CTRB2

COSMIC (genes):CTRB2 CTRB2

CTD Gene:440387 CTRB2

dbSNP Gene:440387 CTRB2

ENSEMBL:ENSG00000168928 CTRB2

HGNC:2522 CTRB2

KEGG:hsa:440387 CTRB2

Monarch:440387 CTRB2

NCBI Gene:440387 CTRB2

OMIM:619620 CTRB2

UCSC:Q6GPI1 CTRB2

Reference Transcript

RefSeq:NM_001025200.3 CTRB2

Other Identifiers

11715688_x_at

11757286_s_at

16828415

205971_PM_s_at

205971_s_at

214411_3p_x_at

214411_PM_x_at

214411_x_at

36141_at

3668925

3668926

3668927

3668928

3668929

3668931

3668932

3668933

3668934

3668935

3668941

3699391

3699392

3699393

3699394

3699395

3699396

3699397

3699398

3699399

3699401

3699402

3699403

3699404

3699405

3699406

3699407

3699408

3699409

3699410

3699411

440387

7997264

8002845

A_23_P431139

A_32_P86150

GO:0003824

GO:0004252

GO:0005576

GO:0006508

GO:0007586

GO:0008236

GO:0016787

GO:0140096

HMNXSV003050947

Hs.74502.1.S1_3p_a_at

Hs.74502.1.S1_3p_x_at

ILMN_1651430

ILMN_1767643

ILMN_2137654

M24400_at

PH_hs_0040247

TC16000617.hg

TC16001275.hg

g4503134_3p_a_at

Participates

as a component of

CTRB2 [extracellular region] (Homo sapiens)

Other forms of this molecule

CTRB2(34-164) [extracellular region]

CTRB2(19-31) [extracellular region]

Inferred To

Ctrb1 [extracellular region] (Mus musculus)

Ctrb1 [extracellular region] (Rattus norvegicus)

LOC121106428 [extracellular region] (Gallus gallus)

Homologues of CTRB1(167-263) [extracellular region] (Danio rerio)

Homologues of CTRB1(167-263) [extracellular region] (Gallus gallus)

CTRB1(167-263) [extracellular region] (Gallus gallus)

CTRB1(167-263) [extracellular region] (Sus scrofa)

ctrb.2 [extracellular region] (Danio rerio)

CTRB1 [extracellular region] (Bos taurus)

CTRB1 [extracellular region] (Canis familiaris)

Ghost homologue of CTRB2(167-263) [extracellular region] (Xenopus tropicalis)

ctrb.1 [extracellular region] (Danio rerio)

ctrb.3 [extracellular region] (Danio rerio)

Cross References

RefSeq

NP_001020371.3

ENSEMBL

ENST00000303037, ENSG00000168928, ENSP00000303963

OpenTargets

ENSG00000168928

GeneCards

CTRB2

HPA

ENSG00000168928-CTRB2

PRO

Q6GPI1

Pharos - Targets

Q6GPI1