PC is hydrolyzed to 1-acyl LPC by PLB1

Stable Identifier
R-HSA-1602399
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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At the plasma membrane, phosphatidylcholine (PC) is hydrolyzed, removing one of its acyl groups, to 1-acyl lysophosphatidylcholine (LPC) by membrane-associated phospholipase B1 (PLB1) (Maury et al. 2002, Gassama-Diagne et al. 1992).

Literature References
PubMed ID Title Journal Year
1618844 Substrate specificity of phospholipase B from guinea pig intestine. A glycerol ester lipase with broad specificity

Gassama-Diagne, A, Rogalle, P, Fauvel, J, Willson, M, Klaébé, A, Chap, H

J Biol Chem 1992
12150957 Human epidermis is a novel site of phospholipase B expression

Maury, E, Prévost, MC, Nauze, M, Redoulès, D, Tarroux, R, Charvéron, M, Salles, JP, Perret, B, Chap, H, Gassama-Diagne, A

Biochem Biophys Res Commun 2002
Participants
Participates
Catalyst Activity

phospholipase A2 activity of PLB1 [plasma membrane]

Orthologous Events
Authored
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