PC is hydrolyzed to 1-acyl LPC by PLB1

Stable Identifier
R-HSA-1602399
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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At the plasma membrane, phosphatidylcholine (PC) is hydrolyzed, removing one of its acyl groups, to 1-acyl lysophosphatidylcholine (LPC) by membrane-associated phospholipase B1 (PLB1) (Maury et al. 2002, Gassama-Diagne et al. 1992).
Literature References
PubMed ID Title Journal Year
12150957 Human epidermis is a novel site of phospholipase B expression

Redoulès, D, Salles, JP, Prévost, MC, Tarroux, R, Nauze, M, Gassama-Diagne, A, Perret, B, Charvéron, M, Maury, E, Chap, H

Biochem Biophys Res Commun 2002
1618844 Substrate specificity of phospholipase B from guinea pig intestine. A glycerol ester lipase with broad specificity

Fauvel, J, Klaébé, A, Gassama-Diagne, A, Rogalle, P, Chap, H, Willson, M

J Biol Chem 1992
Participants
Participates
Catalyst Activity

phospholipase A2 activity of PLB1 [plasma membrane]

Orthologous Events
Authored
Created
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