crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen

Stable Identifier
R-HSA-158756
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

At the beginning of this reaction, 1 molecule of 'plasminogen', and 1 molecule of 'fibrin multimer, crosslinked:tissue plasminogen activator (two-chain)' are present. At the end of this reaction, 1 molecule of 'fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen' is present.

This reaction takes place in the 'extracellular region'.

Literature References
PubMed ID Title Journal Year
2962641 Interaction of one-chain and two-chain tissue plasminogen activator with intact and plasmin-degraded fibrin

Higgins, DL, Vehar, GA

Biochemistry 1987
Participants
Participant Of
Orthologous Events
Created