Reactome | factor XIa heavy chain [plasma membrane]

factor XIa heavy chain [plasma membrane]

Stable Identifier

R-HSA-158263

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

F11

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P03951 F11

Gene Names

F11

Chain

signal peptide:1-18, chain:19-387, chain:388-625

Reference Genes

BioGPS Gene:2160 F11

COSMIC (genes):F11 F11

CTD Gene:2160 F11

dbSNP Gene:2160 F11

ENSEMBL:ENSG00000088926.14 F11

HGNC:3529 F11

KEGG Gene (Homo sapiens):2160 F11

Monarch:2160 F11

NCBI Gene:2160 F11

OMIM:264900 F11

UCSC:P03951 F11

Reference Transcript

RefSeq:NM_000128.3 F11

Other Identifiers

11734932_at

11752521_a_at

16973085

206610_PM_s_at

206610_s_at

2160

235915_PM_at

235915_at

2755155

2755157

2755159

2755161

2755162

2755164

2755166

2755169

2755170

2755172

2755176

2755177

2755178

2755179

2755182

2755185

2755187

2755188

2755190

35591_at

50929_at

8098671

A_14_P123055

A_23_P41314

A_33_P3378556

GE80292

GO:0003824

GO:0004252

GO:0005515

GO:0005576

GO:0005615

GO:0005886

GO:0006508

GO:0007596

GO:0007599

GO:0008201

GO:0008233

GO:0008236

GO:0016020

GO:0016787

GO:0030193

GO:0031639

GO:0042060

GO:0042802

GO:0043226

GO:0051604

GO:0051919

GO:0070009

GO:0070062

GO:0140096

HMNXSV003000031

HMNXSV003049643

Hs.34226.0.A1_3p_at

ILMN_1764061

ILMN_1807101

M20218_at

PH_hs_0000193

TC04000916.hg

g9961351_3p_a_at

Participates

as a component of

factor XIa [plasma membrane] (Homo sapiens)

Other forms of this molecule

factor XIa light chain [plasma membrane]

factor XI monomer [plasma membrane]

factor XI monomer [extracellular region]

Inferred To

klkb1 [plasma membrane] (Xenopus tropicalis)

F11 [plasma membrane] (Bos taurus)

F11 [plasma membrane] (Rattus norvegicus)

F11 [plasma membrane] (Sus scrofa)

factor XIa heavy chain [plasma membrane] (Danio rerio)

factor XIa heavy chain [plasma membrane] (Gallus gallus)

factor XIa heavy chain [plasma membrane] (Mus musculus)

Cross References

RefSeq

NP_000119.1

Guide to Pharmacology - Targets

2360

OpenTargets

ENSG00000088926

ZINC - Substances

FA11_HUMAN

ZINC target

P03951

PRO

P03951

PDB

5QTV, 6R8X, 4X6P, 2F83, 5QTW, 6TWB, 6AOD, 1ZHP, 1ZOM, 4D7G, 1ZHM, 5QTT, 1XX9, 2J8J, 5EOD, 5EXN, 1ZHR, 5EXM, 3SOS, 5QTY, 4D76, 5EOK, 1ZPC, 4X6M, 2J8L, 7CJ1, 1ZPB, 3SOR, 5TKT, 4TY6, 3BG8, 4X6O, 6HHC, 4X6N, 1ZJD, 1ZPZ, 5Q0D, 5EXL, 4D7F, 1ZRK, 6W50, 5TKS, 4TY7, 6VLV, 7V17, 5Q0G, 5Q0F, 1ZTL, 7V18, 5Q0H, 5Q0E, 5I25, 1ZSK, 1ZSJ, 6VLU, 4WXI, 6TS7, 2FDA, 7V12, 1ZSL, 7V14, 5TKU, 5QQO, 7V13, 7V10, 6USY, 7V11, 7V0Z, 1ZTK, 4CRB, 6C0S, 1ZLR, 6TS4, 4Y8Z, 1ZTJ, 4CRE, 5QQP, 1XXF, 7V16, 4CRD, 5WB6, 7V15, 4CRC, 5E2P, 4CRG, 5QCK, 4CR5, 5QCL, 4CRF, 5QCM, 1ZMJ, 7MBO, 4Y8Y, 6I58, 6TS5, 4CR9, 4Y8X, 1ZML, 4NA8, 6TS6, 1ZMN, 4NA7, 1XXD, 5E2O, 4CRA, 5QCN

GeneCards

P03951

HPA

ENSG00000088926-F11

Ensembl

ENSG00000088926, ENST00000264692, ENSP00000384957, ENST00000403665, ENSP00000264692

Pharos - Targets

P03951

Orphanet

16009

ZINC - Predictions - Purchasable

FA11_HUMAN