PSEN2 [plasma membrane]

Stable Identifier
R-HSA-157352
Type
Complex
Species
Homo sapiens
Compartment
Synonyms
PSEN2 dimer, Presenilin-2
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
15147205 Mechanism of gamma-secretase cleavage activation: is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop?

Knappenberger, KS, Tian, G, Ye, X, Sobotka-Briner, C, Ghanekar, SV, Greenberg, BD, Scott, CW

Biochemistry 2004
24781550 Therapeutic modulation of Notch signalling--are we there yet?

Andersson, ER, Lendahl, U

Nat Rev Drug Discov 2014
20445084 Structural investigation of the C-terminal catalytic fragment of presenilin 1

Sobhanifar, S, Schneider, B, Löhr, F, Gottstein, D, Ikeya, T, Mlynarczyk, K, Pulawski, W, Ghoshdastider, U, Kolinski, M, Filipek, S, Güntert, P, Bernhard, F, Dötsch, V

Proc. Natl. Acad. Sci. U.S.A. 2010
Participants
Participant Of
Inferred To