At the endoplasmic reticulum (ER) membrane, triacylglycerol (TAG) is hydrolyzed, removing one of its acyl groups to form diacylglycerol (DAG) by patatin-like phospholipase domain-containing protein 2/3 (PNPLA2/3) (He et al. 2010, Jenkins et al. 2004, Basantani et al. 2011).
Kershaw, EE, Schoiswohl, G, Gardner, NP, Yang, K, Basantani, MK, Sitnick, MT, Gross, RW, Li, JZ, Brenner, DS, Zechner, R, Cai, L, Kumari, M
Garuti, R, Hobbs, HH, Kinch, L, McPhaul, C, Cohen, JC, Li, JZ, Grishin, NV, He, S
Gibson, B, Yan, W, Sims, HF, Gross, RW, Jenkins, CM, Mancuso, DJ
triglyceride lipase activity of PNPLA2/3 [endoplasmic reticulum membrane]
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