1-acyl LPI is acylated to PI by MBOAT7

Stable Identifier
R-HSA-1482598
Type
Reaction
Species
Homo sapiens
Compartment
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At the endoplasmic reticulum (ER) membrane, lysophospholipid acyltransferase 7 (MBOAT7) aka LPIAT acylates 1-acyl lysophosphatidylinositol (LPI) to form phosphatidylinositol (PI) (Gijon et al. 2008, Lee et al. 2008).

Literature References
PubMed ID Title Journal Year
18772128 Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils

Zarini, S, Voelker, DR, Riekhof, WR, Gijon, MA, Murphy, RC

J Biol Chem 2008
18094042 Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol

Kono, N, Matsuda, S, Mitani, S, Arai, H, Gengyo-Ando, K, Inoue, T, Lee, HC, Imae, R, Shirae, S

Mol Biol Cell 2008
Participants
Participates
Catalyst Activity

1-acylglycerol-3-phosphate O-acyltransferase activity of MBOAT7 [endoplasmic reticulum membrane]

Orthologous Events
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