Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Core 4 (MUC15) [Golgi lumen]
Stable Identifier
R-HSA-1462257
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
MUC15, MUC15_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Homo sapiens)
Core 4 mucins [Golgi lumen] (Homo sapiens)
Core 4 (MUC15) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N387 MUC15
Gene Names
MUC15, UNQ750/PRO1481
Chain
signal peptide:1-23, chain:24-334
Reference Genes
BioGPS Gene:143662 MUC15
COSMIC (genes):MUC15 MUC15
CTD Gene:143662 MUC15
dbSNP Gene:143662 MUC15
ENSEMBL:ENSG00000169550 MUC15
ENSEMBL_homo_sapiens_GENE:ENSG00000169550.14 MUC15
HGNC:14956 MUC15
KEGG Gene (Homo sapiens):143662 MUC15
Monarch:143662 MUC15
NCBI Gene:143662 MUC15
OMIM:608566 MUC15
UCSC:Q8N387 MUC15
Reference Transcript
RefSeq:NM_145650.3 MUC15
RefSeq:NM_001135092.1 MUC15
RefSeq:NM_001135091.1 MUC15
Other Identifiers
11724257_a_at
11724258_a_at
143662
16736764
227238_PM_at
227238_at
227241_PM_at
227241_at
3366904
3366905
3366906
3366907
3366909
3366910
3366913
43536_at
44236_r_at
47072_at
62573_at
7947156
84240_at
A_23_P24332
GE80513
GO:0005515
GO:0005576
GO:0005794
GO:0005796
GO:0005886
GO:0016020
GO:0043226
HMNXSV003057409
Hs.24139.0.S1_3p_at
Hs.24139.0.S2_3p_at
ILMN_1793537
PH_hs_0002132
TC11001505.hg
Participates
as a member of
Core 4 mucins [Golgi lumen] (Homo sapiens)
Other forms of this molecule
Core 8 (MUC15) [Golgi lumen]
Core 2S (MUC15) [Golgi lumen]
Core 5 (MUC15) [Golgi lumen]
Core 3 (MUC15) [Golgi lumen]
Core 7 (MUC15) [Golgi lumen]
extended Core 6 (MUC15) [Golgi lumen]
GalNAc-MUC15 [plasma membrane]
Core 2 (MUC15) [Golgi lumen]
Core 2a (MUC15) [Golgi lumen]
GalNAc-MUC15 [Golgi lumen]
Sialyl Tn antigen (MUC15) [Golgi lumen]
T-antigen (MUC15) [Golgi lumen]
Sialyl-2,3 T-antigen (MUC15) [Golgi lumen]
Sialyl T-antigen (MUC15) [Golgi lumen]
Disialyl T-antigen (MUC15) [Golgi lumen]
MUC15 [Golgi lumen]
Core 6 (MUC15) [Golgi lumen]
Inferred To
Muc15 [Golgi lumen]
(Mus musculus)
Muc15 [Golgi lumen]
(Rattus norvegicus)
MUC15 [Golgi lumen]
(Bos taurus)
MUC15 [Golgi lumen]
(Canis familiaris)
MUC15 [Golgi lumen]
(Sus scrofa)
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine (GlcNAc-beta1,3(GlcNAc-beta1,6)GalNac-alpha group) at unknown position
Modification
GlcNAc-beta1,3(GlcNAc-beta1,6)GalNac-alpha group
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_001128563.1
,
NP_001128564.1
,
NP_663625.2
OpenTargets
ENSG00000169550
HPA
ENSG00000169550-MUC15
GeneCards
Q8N387
Ensembl
ENST00000455601
,
ENSG00000169550
,
ENSP00000397339
PRO
Q8N387
Pharos - Targets
Q8N387
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text