Deubiquitination of RNF41 by P-USP8

Stable Identifier
R-HSA-1358795
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Phosphorylated USP8 deubiquitinates RNF41 and increases RNF41 level in the cell.

Literature References
PubMed ID Title Journal Year
17210635 Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1

Cao, Z, Wu, X, Yen, L, Sweeney, C, Carraway KL, 3rd

Mol Cell Biol 2007
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
thiol-dependent ubiquitin-specific protease activity of Ub-RNF41:p-USP8 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created