Deubiquitination of RNF41 by P-USP8

Stable Identifier
R-HSA-1358795
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Deubiquitination of RNF41 by P-USP8
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Phosphorylated USP8 deubiquitinates RNF41 and increases RNF41 level in the cell.
Literature References
PubMed ID Title Journal Year
17210635 Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1

Carraway KL, 3rd, Cao, Z, Sweeney, C, Wu, X, Yen, L

Mol Cell Biol 2007
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Output
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as an event of
Catalyst Activity

cysteine-type deubiquitinase activity of Ub-RNF41:p-USP8 [cytosol]

Physical Entity
Ub-RNF41:p-USP8 [cytosol] (Homo sapiens)
Activity
cysteine-type deubiquitinase activity (GO:0004843)
Orthologous Events
Deubiquitination of RNF41 by P-USP8 (Bos taurus)
Deubiquitination of RNF41 by P-USP8 (Dictyostelium discoideum)
Deubiquitination of RNF41 by P-USP8 (Drosophila melanogaster)
Deubiquitination of RNF41 by P-USP8 (Gallus gallus)
Deubiquitination of RNF41 by P-USP8 (Mus musculus)
Deubiquitination of RNF41 by P-USP8 (Rattus norvegicus)
Deubiquitination of RNF41 by P-USP8 (Sus scrofa)
Authored
Orlic-Milacic, M  (2011-11-04)
Reviewed
Neckers, LM  (2011-11-11)
Xu, W  (2011-11-11)
Created
Orlic-Milacic, M  (2011-06-02)
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