RNF41 ubiquitinates ERBB3

Stable Identifier
R-HSA-1358790
Type
Reaction
Species
Homo sapiens
Compartment
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RNF41 ubiquitinates unstimulated ERBB3, targeting it for degradation and regulating ERBB3 level in the cell.

Literature References
PubMed ID Title Journal Year
17210635 Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1

Carraway KL, 3rd, Cao, Z, Sweeney, C, Wu, X, Yen, L

Mol Cell Biol 2007
Participants
Participates
Catalyst Activity

ubiquitin-protein transferase activity of ERBB3:RNF41 [plasma membrane]

Orthologous Events
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