Self-ubiquitination of RNF41

Stable Identifier
R-HSA-1358789
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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Self-ubiquitination of RNF41
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RNF41 is able to self-ubiquitinate, which keeps its levels low when ERBB3 is unstimulated.

Literature References
PubMed ID Title Journal Year
12411582 Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3

Qiu, XB, Goldberg, AL

Proc Natl Acad Sci U S A 2002
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
ubiquitin-protein transferase activity of RNF41 [cytosol]
Physical Entity
RNF41 [cytosol]
Activity
ubiquitin-protein transferase activity (0004842)
Orthologous Events
Self-ubiquitination of RNF41 (Bos taurus)
Self-ubiquitination of RNF41 (Canis familiaris)
Self-ubiquitination of RNF41 (Danio rerio)
Self-ubiquitination of RNF41 (Dictyostelium discoideum)
Self-ubiquitination of RNF41 (Drosophila melanogaster)
Self-ubiquitination of RNF41 (Gallus gallus)
Self-ubiquitination of RNF41 (Mus musculus)
Self-ubiquitination of RNF41 (Rattus norvegicus)
Self-ubiquitination of RNF41 (Sus scrofa)
Self-ubiquitination of RNF41 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2011-11-04)
Reviewed
Neckers, LM  (2011-11-11)
Xu, W  (2011-11-11)
Created
Orlic-Milacic, M  (2011-06-02)