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TRPC6 [plasma membrane]
Stable Identifier
R-HSA-1297324
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Short transient receptor potential channel 6, TRPC6_HUMAN, Transient receptor potential channel 6
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Netrin-1 signaling (Homo sapiens)
Role of second messengers in netrin-1 signaling (Homo sapiens)
Activation of TRPC channels by Netrin-1 (Homo sapiens)
Activated TRP channels [plasma membrane] (Homo sapiens)
TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC6 [plasma membrane] (Homo sapiens)
TRPC channels [plasma membrane] (Homo sapiens)
TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC6 [plasma membrane] (Homo sapiens)
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Effects of PIP2 hydrolysis (Homo sapiens)
DAG activation of TRPC channels (Homo sapiens)
DAG-activated TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC6 [plasma membrane] (Homo sapiens)
TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC6 [plasma membrane] (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Platelet calcium homeostasis (Homo sapiens)
Elevation of cytosolic Ca2+ levels (Homo sapiens)
Cation influx mediated by TRPC3/6/7 (Homo sapiens)
DAG-activated TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC6 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Effects of PIP2 hydrolysis (Homo sapiens)
DAG activation of TRPC channels (Homo sapiens)
DAG-activated TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC6 [plasma membrane] (Homo sapiens)
TRPC3/6/7 [plasma membrane] (Homo sapiens)
TRPC6 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
TRP channels (Homo sapiens)
TRPs transport extracellular Ca2+ to cytosol (Homo sapiens)
TRPs [plasma membrane] (Homo sapiens)
TRPC6 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y210 TRPC6
Gene Names
TRPC6, TRP6
Chain
chain:1-931
Reference Genes
BioGPS Gene:7225 TRPC6
COSMIC (genes):TRPC6 TRPC6
CTD Gene:7225 TRPC6
dbSNP Gene:7225 TRPC6
ENSEMBL:ENSG00000137672 TRPC6
ENSEMBL_homo_sapiens_GENE:ENSG00000137672.13 TRPC6
HGNC:12338 TRPC6
KEGG Gene (Homo sapiens):7225 TRPC6
Monarch:7225 TRPC6
NCBI Gene:7225 TRPC6
OMIM:603652 TRPC6
UCSC:Q9Y210 TRPC6
Reference Transcript
RefSeq:XM_017018221.1 TRPC6
RefSeq:NM_004621.5 TRPC6
Other Identifiers
11736871_s_at
11736872_a_at
16743593
206528_PM_at
206528_at
217287_PM_s_at
217287_s_at
3079098
3388439
3388440
3388441
3388443
3388444
3388451
3388452
3388453
3388454
3388457
3388461
3388462
3388465
3388471
3388472
3388484
3388485
3388486
3388487
3388488
36365_at
7225
7951178
A_23_P127547
A_33_P3337627
GE55171
GO:0005215
GO:0005216
GO:0005261
GO:0005262
GO:0005515
GO:0005737
GO:0005886
GO:0006811
GO:0006812
GO:0006816
GO:0007204
GO:0007338
GO:0015279
GO:0016020
GO:0022414
GO:0032414
GO:0034220
GO:0034703
GO:0036057
GO:0042803
GO:0051480
GO:0051928
GO:0055065
GO:0055085
GO:0070588
GO:0070679
HMNXSV003041275
Hs.159003.2.S1_3p_a_at
ILMN_1656410
PH_hs_0009653
TC11002221.hg
TC11003310.hg
g5730101_3p_at
Participates
as a member of
TRPs [plasma membrane] (Homo sapiens)
TRPC3/6/7 [plasma membrane] (Homo sapiens)
Inferred To
trpc6a [plasma membrane]
(Danio rerio)
Trpc6 [plasma membrane]
(Mus musculus)
trpc6 [plasma membrane]
(Xenopus tropicalis)
trp-1 [plasma membrane]
(Caenorhabditis elegans)
TRPC6 [plasma membrane]
(Bos taurus)
TRPC6 [plasma membrane]
(Canis familiaris)
TRPC6 [plasma membrane]
(Gallus gallus)
TRPC6 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
XP_016873710.1
,
NP_004612.2
Guide to Pharmacology - Targets
491
OpenTargets
ENSG00000137672
ZINC - Substances
TRPC6_HUMAN
ZINC target
Q9Y210
PRO
Q9Y210
PDB
6UZ8
,
7A6U
,
5YX9
,
7DXG
,
7DXF
,
6UZA
GeneCards
Q9Y210
HPA
ENSG00000137672-TRPC6
Ensembl
ENST00000348423
,
ENSP00000343672
,
ENSP00000353687
,
ENSG00000137672
,
ENSP00000340913
,
ENST00000344327
,
ENST00000360497
Pharos - Targets
Q9Y210
Orphanet
15665
ZINC - Predictions - Purchasable
TRPC6_HUMAN
HMDB Protein
HMDBP08078
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