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ZNF454 [nucleoplasm]
Stable Identifier
R-HSA-1247868
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Zinc finger protein 454, ZN454_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Regulation of endogenous retroelements (Homo sapiens)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Homo sapiens)
ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Homo sapiens)
ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Homo sapiens)
CBX5:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
KRAB-ZFP binds retroelement DNA in chromatin (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
NuRD complex binds SUMO2-6K-TRIM28:KRAB-ZNF:retroelement (Homo sapiens)
NuRD:SUMO2-6K-TRIM28:KRAB-ZNF:retroelement chromatin [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Homo sapiens)
ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
TRIM28 (KAP1) binds KRAB-ZFP in KRAB-ZFP:retroelement chromatin (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
TRIM28 in TRIM28:KRAB-ZFP:retroelement chromatin autoSUMOylates with SUMO2 (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
KRAB-ZNF / KAP Interaction (Homo sapiens)
KRAB-ZNF / KAP Complex [nucleoplasm] (Homo sapiens)
KRAB-ZNF [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
KRAB-ZNF [nucleoplasm] (Homo sapiens)
ZNF454 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N9F8 ZNF454
Gene Names
ZNF454
Chain
chain:1-522
Reference Genes
BioGPS Gene:285676 ZNF454
COSMIC (genes):ZNF454 ZNF454
CTD Gene:285676 ZNF454
dbSNP Gene:285676 ZNF454
ENSEMBL:ENSG00000178187 ZNF454
HGNC:21200 ZNF454
KEGG:hsa:285676 ZNF454
Monarch:285676 ZNF454
NCBI Gene:285676 ZNF454
UCSC:Q8N9F8 ZNF454
Reference Transcript
RefSeq:NM_001323306.2 ZNF454
RefSeq:NM_001178090.3 ZNF454
RefSeq:NM_182594.4 ZNF454
RefSeq:NM_001178089.3 ZNF454
Other Identifiers
11740453_a_at
16993311
2843842
2843884
2843885
2843886
2843887
2843888
2843889
2843891
2843892
2843893
2843894
2843900
285676
8110478
A_14_P106775
A_23_P144746
GE905468
GO:0000978
GO:0000981
GO:0003677
GO:0005634
GO:0006355
GO:0006357
GO:0008270
GO:0043226
GO:0140110
GO:1990837
HMNXSV003051869
ILMN_1706506
PH_hs_0026247
TC05001038.hg
Participates
as a candidate of
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
KRAB-ZNF [nucleoplasm] (Homo sapiens)
Inferred To
Phs [nucleoplasm]
(Drosophila melanogaster)
Dmel\CG8301 [nucleoplasm]
(Drosophila melanogaster)
Dmel\CG5245 [nucleoplasm]
(Drosophila melanogaster)
Zfp454 [nucleoplasm]
(Mus musculus)
Homologues of ZNF454 [nucleoplasm]
(Drosophila melanogaster)
Homologues of ZNF454 [nucleoplasm]
(Gallus gallus)
ZNF454 [nucleoplasm]
(Bos taurus)
ZNF454 [nucleoplasm]
(Gallus gallus)
ZNF454 [nucleoplasm]
(Sus scrofa)
Meics [nucleoplasm]
(Drosophila melanogaster)
kipf [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001171560.1
,
NP_001310235.1
,
NP_872400.2
,
NP_001171561.1
ENSEMBL
ENST00000519564
,
ENSG00000178187
,
ENST00000320129
,
ENSP00000326249
,
ENSP00000430354
OpenTargets
ENSG00000178187
GeneCards
ZNF454
HPA
ENSG00000178187-ZNF454
PRO
Q8N9F8
Pharos - Targets
Q8N9F8
GlyGen
Q8N9F8
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