Superoxide can enter the bacterium when acidic conditions apply. Together with a proton it forms the uncharged hydroperoxyl radical (OOH·) which is membrane permeable (Nathan & Shiloh 2000, Zahrt & Deretic 2002, Warner & Mizrahi 2006, Spagnolo et al, 2004).
Zahrt, TC, Deretic, V
Warner, DF, Mizrahi, V
D'Orazio, M, Törö, I, Spagnolo, L, Pedersen, JZ, Carugo, O, Rotilio, G, Battistoni, A, Djinovic-Carugo, K, O'Neill, P
Shiloh, MU, Nathan, C
© 2023 Reactome