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Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane]
Stable Identifier
R-HSA-1218825
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by EGFR in Cancer (Homo sapiens)
Signaling by Ligand-Responsive EGFR Variants in Cancer (Homo sapiens)
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants (Homo sapiens)
Binding of EGF to ligand-responsive EGFR mutants (Homo sapiens)
Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Binding of ligand-responsive EGFR mutants to chaperoning proteins HSP90 and CDC37 (Homo sapiens)
Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants (Homo sapiens)
Active dimers of ligand-responsive EGFR mutants [plasma membrane] (Homo sapiens)
Ligand-responsive EGFR mutants dimer [plasma membrane] (Homo sapiens)
Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Spontaneous dimerization of ligand-responsive EGFR mutants (Homo sapiens)
Ligand-responsive EGFR mutants dimer [plasma membrane] (Homo sapiens)
Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers (Homo sapiens)
Active dimers of ligand-responsive EGFR mutants [plasma membrane] (Homo sapiens)
Ligand-responsive EGFR mutants dimer [plasma membrane] (Homo sapiens)
Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Participants
members
Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
(Homo sapiens)
Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
(Homo sapiens)
Participates
as an input of
Binding of EGF to ligand-responsive EGFR mutants (Homo sapiens)
Spontaneous dimerization of ligand-responsive EGFR mutants (Homo sapiens)
as a component of
Ligand-responsive EGFR mutants dimer [plasma membrane] (Homo sapiens)
as an output of
Binding of ligand-responsive EGFR mutants to chaperoning proteins HSP90 and CDC37 (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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