Formation of P-TEFb complex

Stable Identifier
R-HSA-112430
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Formation of P-TEFb complex
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'Cdk 9 protein', 1 molecule of 'Cyclin T1', and 1 molecule of 'Cyclin T2' are present. At the end of this reaction, 1 molecule of 'P-TEFb complex' is present.

This reaction takes place in the 'nucleus'.
Literature References
PubMed ID Title Journal Year
11884399 P-TEFb containing cyclin K and Cdk9 can activate transcription via RNA

Taube, R, Peterlin, BM, Fujinaga, K, Lin, X

J. Biol. Chem. 2002
Participants
Input
Output
Participates
as an event of
Orthologous Events
Formation of P-TEFb complex (Bos taurus)
Formation of P-TEFb complex (Caenorhabditis elegans)
Formation of P-TEFb complex (Canis familiaris)
Formation of P-TEFb complex (Danio rerio)
Formation of P-TEFb complex (Dictyostelium discoideum)
Formation of P-TEFb complex (Drosophila melanogaster)
Formation of P-TEFb complex (Gallus gallus)
Formation of P-TEFb complex (Mus musculus)
Formation of P-TEFb complex (Rattus norvegicus)
Formation of P-TEFb complex (Saccharomyces cerevisiae)
Formation of P-TEFb complex (Schizosaccharomyces pombe)
Formation of P-TEFb complex (Sus scrofa)
Formation of P-TEFb complex (Xenopus tropicalis)
Created
Gopinathrao, G  (2004-05-03)
Cite Us!