(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP

Stable Identifier
R-HSA-110137
Type
Reaction
Species
Homo sapiens
Compartment
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Cytosolic adenylate kinase 5 [AK5] catalyzes the reactions of (d)ADP and (d)CDP with ADP to form (d)AMP and (d)CMP, respectively, and ATP. In the body AK5 expression was observed only in brain of nine tissues tested by Northern blotting (Van Rompay et al. 1999). AK5 is inferred to occur as a dimer from unpublished crystallographic data obtained for the catalytically active carboxyterminal third of the protein (PDB 2BWJ).

Literature References
Participants
Participates
Catalyst Activity

nucleoside kinase activity of AK5,7,8,9 [cytosol]

Orthologous Events
Cross References
Rhea
Created
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