Factor H (CFH) preferentially binds to host cells and surfaces that have negatively charged cell surface polyanions such as heparin and sialic acid commonly found on host cells (Kazatchkine et al. 1979, Meri & Pangburn 1990). This mediates protection of plasma-exposed host structures.
Remuzzi, G, Jòzsi, M, Seeberger, H, Gordon, DL, Noris, M, Cheng, ZZ, Jokiranta, TS, Heinen, S, Hellwage, J, Meri, S, Zipfel, PF, Ormsby, R
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