CD46 binds C3b

Stable Identifier
R-HSA-1006143
Type
Reaction
Species
Homo sapiens
Compartment
plasma membrane
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CD46 binds C3b
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Membrane cofactor protein (MCP; CD46) is a widely distributed C3b/C4b-binding cell surface glycoprotein which is a cofactor for Complement factor I.

Literature References
PubMed ID Title Journal Year
2481448 Functional properties of membrane cofactor protein of complement

Seya, T, Atkinson, JP

Biochem J 1989
12055245 Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells

Barilla-LaBarca, ML, Liszewski, MK, Lambris, JD, Hourcade, D, Atkinson, JP

J Immunol 2002
Participants
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Output
Participant Of
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Orthologous Events
CD46 binds C3b (Caenorhabditis elegans)
CD46 binds C3b (Canis familiaris)
CD46 binds C3b (Danio rerio)
CD46 binds C3b (Gallus gallus)
CD46 binds C3b (Mus musculus)
CD46 binds C3b (Rattus norvegicus)
CD46 binds C3b (Xenopus tropicalis)
Authored
Jupe, S  (2010-11-09)
Reviewed
Bradley, DT  (2012-02-13)
Fraczek, LA  (2012-02-13)
Created
Jupe, S  (2010-11-10)
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