CD46 binds C3b

Stable Identifier
R-HSA-1006143
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
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CD46 binds C3b
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Membrane cofactor protein (MCP; CD46) is a widely distributed C3b/C4b-binding cell surface glycoprotein which is a cofactor for Complement factor I.

Literature References
PubMed ID Title Journal Year
12055245 Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells

Atkinson, JP, Barilla-LaBarca, ML, Lambris, JD, Liszewski, MK, Hourcade, D

J Immunol 2002
2481448 Functional properties of membrane cofactor protein of complement

Atkinson, JP, Seya, T

Biochem J 1989
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Authored
Jupe, S  (2010-11-09)
Reviewed
Fraczek, LA  (2012-02-13)
Bradley, DT  (2012-02-13)
Created
Jupe, S  (2010-11-10)
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