Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
CD274 [endoplasmic reticulum membrane]
Stable Identifier
R-GGA-9931256
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
endoplasmic reticulum membrane
Synonyms
E1C153
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Regulation of T cell activation by CD28 family (Gallus gallus)
Co-inhibition by PD-1 (Gallus gallus)
Regulation of PD-L1(CD274) expression (Gallus gallus)
Regulation of PD-L1(CD274) Post-translational modification (Gallus gallus)
GSK3B-mediated proteasomal degradation of PD-L1(CD274) (Gallus gallus)
GSK3B phosphorylates CD274 (Gallus gallus)
CD274 [endoplasmic reticulum membrane] (Gallus gallus)
PD-L1(CD274) glycosylation and translocation to plasma membrane (Gallus gallus)
CD274 N-linked glycosylation in ER (Gallus gallus)
CD274 [endoplasmic reticulum membrane] (Gallus gallus)
Transport of N-glycosylated CD274 to Golgi (Gallus gallus)
CD274 [endoplasmic reticulum membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1C153
Gene Names
CD274
Reference Genes
BioGPS Gene:427224 CD274
ENSEMBL:ENSGALG00010012871.1
Monarch:427224 CD274
NCBI Gene:427224 CD274
UCSC:E1C153 CD274
Reference Transcript
RefSeq:XM_424811.8 CD274
Other Identifiers
427224
GO:0002376
GO:0005886
GO:0006955
GO:0007166
GO:0009897
GO:0016020
GO:0031295
GO:0042102
GO:0042130
GO:0071222
GT_A_87_P003125
GT_A_87_P092406
Gga.12462.1.S1_at
GgaAffx.24574.1.S1_at
Participates
as an input of
Transport of N-glycosylated CD274 to Golgi (Gallus gallus)
as an output of
CD274 N-linked glycosylation in ER (Gallus gallus)
This entity regulates
Negatively
GSK3B phosphorylates CD274
(Gallus gallus)
Other forms of this molecule
CD274 [plasma membrane]
CD274 [plasma membrane]
CD274 [Golgi membrane]
CD274 [Golgi membrane]
CD274 [Golgi membrane]
phospho-CD274 [endoplasmic reticulum membrane]
phospho-CD274 [endoplasmic reticulum membrane]
CD274 [cytosol]
phospho-CD274 [cytosol]
phospho-CD274 [endoplasmic reticulum membrane]
phospho-CD274 [endoplasmic reticulum membrane]
CD274 [endoplasmic reticulum membrane]
phospho-CD274 [cytosol]
phospho-CD274 [endoplasmic reticulum membrane]
Inferred From
N-glycosylated CD274 [endoplasmic reticulum membrane]
(Homo sapiens)
Modified Residues
Name
N-glycosylated residue at 192 (in Homo sapiens)
Coordinate
192
PsiMod Name
N-glycosylated residue
PsiMod Definition
A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond.
Name
N-glycosylated residue at 200 (in Homo sapiens)
Coordinate
200
PsiMod Name
N-glycosylated residue
PsiMod Definition
A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond.
Name
N-glycosylated residue at 219 (in Homo sapiens)
Coordinate
219
PsiMod Name
N-glycosylated residue
PsiMod Definition
A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond.
Cross References
RefSeq
XP_424811.5
ENSEMBL
ENSGALT00010030875
,
ENSGALP00010017919
,
ENSGALG00010012871
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text