Reactome | Ub,p-T,S-SMAD2/3 [nucleoplasm]

Ub,p-T,S-SMAD2/3 [nucleoplasm]

Stable Identifier

R-GGA-9773846

Type

Set [DefinedSet]

Species

Gallus gallus

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Gene expression (Transcription) (Gallus gallus)

- RNA Polymerase II Transcription (Gallus gallus)
  - Generic Transcription Pathway (Gallus gallus)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Gallus gallus)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Gallus gallus)
        
        SMURF2 monoubiquitinates SMAD3 (Gallus gallus)
        
        Ub,p-T,S-SMAD2/3 [nucleoplasm] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Signaling by TGFB family members (Gallus gallus)
  - Signaling by TGF-beta Receptor Complex (Gallus gallus)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Gallus gallus)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Gallus gallus)
        
        SMURF2 monoubiquitinates SMAD3 (Gallus gallus)
        
        Ub,p-T,S-SMAD2/3 [nucleoplasm] (Gallus gallus)

Participants

members

Participates

as an output of

SMURF2 monoubiquitinates SMAD3 (Gallus gallus)

Inferred From

Ub,p-T,S-SMAD2/3 [nucleoplasm] (Homo sapiens)

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