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STUB1 [cytosol]
Stable Identifier
R-GGA-975970
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
STUB1, Q5ZHY5
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional regulation by RUNX2 (Gallus gallus)
Regulation of RUNX2 expression and activity (Gallus gallus)
RUNX2 binds STUB1 (Gallus gallus)
RUNX2:STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1 polyubiquitinates RUNX2 (Gallus gallus)
RUNX2:STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
Interaction of E3 with substrate and E2-Ub complex (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
Polyubiquitination of substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
Release of E3 from polyubiquitinated substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
RIPK1 binds STUB1 (Gallus gallus)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Gallus gallus)
STUB1:STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1:STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Gallus gallus)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Gallus gallus)
STUB1:STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1:STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
PTEN Regulation (Gallus gallus)
Regulation of PTEN stability and activity (Gallus gallus)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Gallus gallus)
NEDD4,STUB1,WWP2 and XIAP [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by ERBB2 (Gallus gallus)
Downregulation of ERBB2 signaling (Gallus gallus)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
Signaling by TGFB family members (Gallus gallus)
Signaling by TGF-beta Receptor Complex (Gallus gallus)
TGF-beta receptor signaling activates SMADs (Gallus gallus)
Downregulation of TGF-beta receptor signaling (Gallus gallus)
SMAD3 binds STUB1 (CHIP) (Gallus gallus)
SMAD3:STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1 (CHIP) ubiquitinates SMAD3 (Gallus gallus)
SMAD3:STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
STUB1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q5ZHY5
Gene Names
STUB1
Reference Genes
BioGPS Gene:426918 STUB1
ENSEMBL:ENSGALG00000041432
KEGG:gga:426918 STUB1
Monarch:426918 STUB1
NCBI Gene:426918 STUB1
UCSC:Q5ZHY5 STUB1
Reference Transcript
RefSeq:NM_001031406.2 STUB1
Participates
as an output of
STUB1 polyubiquitinates RUNX2 (Gallus gallus)
STUB1 (CHIP) ubiquitinates SMAD3 (Gallus gallus)
as an input of
RUNX2 binds STUB1 (Gallus gallus)
SMAD3 binds STUB1 (CHIP) (Gallus gallus)
as a component of
RUNX2:STUB1 [cytosol] (Gallus gallus)
STUB1:STUB1 [cytosol] (Gallus gallus)
SMAD3:STUB1 [cytosol] (Gallus gallus)
as a member of
NEDD4,STUB1,WWP2 and XIAP [cytosol] (Gallus gallus)
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
Inferred From
STUB1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001026577.1
PRO
Q5ZHY5
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