Reactome | UPF2 [cytosol]

UPF2 [cytosol]

Stable Identifier

R-GGA-927799

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

UPF2, A0A8V0XJ43

Locations in the PathwayBrowser

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Metabolism of RNA (Gallus gallus)

- Nonsense-Mediated Decay (NMD) (Gallus gallus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Gallus gallus)
        
        UPF2 [cytosol] (Gallus gallus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Gallus gallus)
        
        UPF2 [cytosol] (Gallus gallus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Gallus gallus)
        
        UPF2 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0XJ43

Gene Names

UPF2

Reference Genes

ENSEMBL:ENSGALG00010005814.1

UCSC:A0A8V0XJ43 UPF2

Other Identifiers

419100

GO:0000184

GO:0001889

GO:0003723

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0031100

GO:0035145

GO:0036464

GO:0042162

GO:0043226

GO:0048471

GO:0048856

GT_A_87_P120438

GT_Xhyb_Chicken_CN222624_2437

Gga.12989.1.S1_at

Gga.17396.1.S1_at

GgaAffx.4167.1.S1_at

GgaAffx.4170.1.S1_at

GgaAffx.42.1.S1_s_at

Participates

as a component of

Exon Junction:UPF2:UPF3 Complex [cytosol] (Gallus gallus)

Inferred From

UPF2 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSGALT00010013862, ENSGALG00010005814, ENSGALP00010008183

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