Reactome | IL7R [clathrin-coated endocytic vesicle membrane]

IL7R [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-GGA-9028500

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

IL7R, A1EA95

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Gallus gallus)

- Membrane Trafficking (Gallus gallus)
  - Clathrin-mediated endocytosis (Gallus gallus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - RAB5 and GAPVD1 bind AP-2 (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        IL7R [clathrin-coated endocytic vesicle membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A1EA95

Gene Names

IL7R

Reference Genes

BioGPS Gene:426054 IL7R

ENSEMBL:ENSGALG00010012726.1

KEGG:gga:426054 IL7R

Monarch:426054 IL7R

NCBI Gene:426054 IL7R

UCSC:A1EA95 IL7R

Reference Transcript

RefSeq:NM_001080106.2 IL7R

Other Identifiers

426054

GO:0000902

GO:0001782

GO:0001913

GO:0001915

GO:0002376

GO:0004896

GO:0004917

GO:0005515

GO:0005654

GO:0005829

GO:0005886

GO:0008284

GO:0008361

GO:0009897

GO:0010467

GO:0010628

GO:0016020

GO:0019221

GO:0019725

GO:0030097

GO:0030154

GO:0030217

GO:0033077

GO:0033089

GO:0038111

GO:0042100

GO:0043029

GO:0046427

GO:0048856

GO:0050830

GO:0070233

GO:0098542

GO:1904894

GT_A_87_P059031

GT_A_87_P265438

GgaAffx.24185.1.S1_at

GgaAffx.8515.1.S1_at

Participates

as a member of

AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)

Other forms of this molecule

IL7R [plasma membrane]

phospho-IL7R [plasma membrane]

Inferred From

IL7R [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_001073575.1

ENSEMBL

ENSGALT00010030459, ENSGALG00010012726, ENSGALP00010017668

PRO

A1EA95

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