Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
Stable Identifier
R-GGA-8875180
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
F1P040
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by MET (Gallus gallus)
Negative regulation of MET activity (Gallus gallus)
CBL monoubiquitinates activated MET (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer [plasma membrane] (Gallus gallus)
HGF dimer:MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
CBL recruits CIN85:endophilin to ubiquitinated MET (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer [plasma membrane] (Gallus gallus)
HGF dimer:MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer [plasma membrane] (Gallus gallus)
HGF dimer:MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
EPS15 and HGS bind ubiquitinated MET (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1) [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer [plasma membrane] (Gallus gallus)
HGF dimer:MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM) [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1) [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer [plasma membrane] (Gallus gallus)
HGF dimer:MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1P040
Reference Genes
ENSEMBL:ENSGALG00000036883
UCSC:F1P040
Participates
as a component of
HGF dimer:MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (Gallus gallus)
Other forms of this molecule
phospho-p-Y1349,Y1356-MET [plasma membrane]
phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
phospho-p-Y1234,Y1235,Y1356-MET [plasma membrane]
phospho-p-Y1003,4Y-MET [plasma membrane]
MET [plasma membrane]
phospho-p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
Inferred From
MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 1003 (in Homo sapiens)
Coordinate
1003
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1234 (in Homo sapiens)
Coordinate
1234
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1235 (in Homo sapiens)
Coordinate
1235
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1349 (in Homo sapiens)
Coordinate
1349
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1356 (in Homo sapiens)
Coordinate
1356
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
ubiquitinylated lysine (Ub [cytosol]) at unknown position
Modification
Ub [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text