Reactome | GAPVD1 [cytosol]

GAPVD1 [cytosol]

Stable Identifier

R-GGA-8871123

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

GAPVD1, A0A3Q2TVQ8

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Gallus gallus)

- Membrane Trafficking (Gallus gallus)
  - Clathrin-mediated endocytosis (Gallus gallus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        GAPVD1 [cytosol] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        GAPVD1 [cytosol] (Gallus gallus)
    - RAB5 and GAPVD1 bind AP-2 (Gallus gallus)
      - GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        GAPVD1 [cytosol] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        GAPVD1 [cytosol] (Gallus gallus)
  - Rab regulation of trafficking (Gallus gallus)
    - RAB GEFs exchange GTP for GDP on RABs (Gallus gallus)
      - RAB5 GEFs exchange GTP for GDP on RAB5 (Gallus gallus)
        
        RAB5 GEFs [cytosol] (Gallus gallus)
        
        GAPVD1 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A3Q2TVQ8

Gene Names

GAPVD1

Reference Genes

BioGPS Gene:417095 GAPVD1

ENSEMBL:ENSGALG00010027973.1

Monarch:417095 GAPVD1

NCBI Gene:417095 GAPVD1

UCSC:A0A3Q2TVQ8 GAPVD1

Reference Transcript

Other Identifiers

417095

GO:0005085

GO:0005096

GO:0005768

GO:0005829

GO:0005886

GO:0006897

GO:0016020

GO:0016192

GO:0030139

GO:0031267

GO:0031410

GO:0032794

GO:0043087

GO:0051223

GO:0098772

GT_A_87_P012430

GT_A_87_P015847

GT_A_87_P116773

GT_Sp_Chicken_CO762376_7829

Gga.10309.1.S1_s_at

Gga.10309.2.S1_s_at

Gga.16684.1.S1_at

Gga.19056.1.S1_at

GgaAffx.22778.1.S1_at

Participates

as a member of

RAB5 GEFs [cytosol] (Gallus gallus)

as a component of

Inferred From

GAPVD1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_046784781.1, XP_046784780.1, XP_015134890.1, XP_040504974.1, XP_046784782.1, XP_046784784.1, XP_040504975.1, XP_046757668.1, XP_046757669.1, XP_046784785.1, XP_046784783.1, XP_046784790.1, XP_046784792.1, XP_015134881.1, XP_046784791.1, XP_025011809.1, XP_046757667.1, XP_046784786.1, XP_046757665.1, XP_046757663.1, XP_046757666.1, XP_046757661.1, XP_046757664.1, XP_046757662.1, XP_046784788.1, XP_046784787.1, XP_046784789.1

ENSEMBL

ENSGALT00010067790, ENSGALG00010027973, ENSGALP00010041533