Reactome | FNBP1L [cytosol]

FNBP1L [cytosol]

Stable Identifier

R-GGA-8867730

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

FNBP1L, A0A8V0ZIW4

Locations in the PathwayBrowser

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Vesicle-mediated transport (Gallus gallus)

- Membrane Trafficking (Gallus gallus)
  - Clathrin-mediated endocytosis (Gallus gallus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
    - Endophilins recruit synaptojanins to the clathrin-coated pit (Gallus gallus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
    - RAB5 and GAPVD1 bind AP-2 (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
    - SNX9 recruits components of the actin polymerizing machinery (Gallus gallus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
    - SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
        
        FNBP1L dimer [cytosol] (Gallus gallus)
        
        FNBP1L [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0ZIW4

Gene Names

FNBP1L

Reference Genes

ENSEMBL:ENSGALG00010021254.1

UCSC:A0A8V0ZIW4 FNBP1L

Other Identifiers

424495

GO:0005515

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005938

GO:0006897

GO:0006900

GO:0006914

GO:0007165

GO:0008289

GO:0010324

GO:0016020

GO:0016050

GO:0016192

GO:0030050

GO:0031410

GO:0044782

GO:0051020

GO:0051491

GO:0060271

GO:0061024

GO:0072583

GO:0097320

GT_A_87_P014921

GT_A_87_P023233

GT_A_87_P078926

GT_A_87_P118268

GT_Sp_Chicken_CO763672_8378

Gga.17030.1.S1_at

Gga.3043.1.S1_at

Participates

as a component of

FNBP1L dimer [cytosol] (Gallus gallus)

Inferred From

FNBP1L [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSGALG00010021254, ENSGALP00010030720, ENSGALT00010051529

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