Reactome | RPL38 [cytosol]

RPL38 [cytosol]

Stable Identifier

R-GGA-72470

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

RPL38, E1BU66

Locations in the PathwayBrowser

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Metabolism of RNA (Gallus gallus)

- Nonsense-Mediated Decay (NMD) (Gallus gallus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL38 [cytosol] (Gallus gallus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL38 [cytosol] (Gallus gallus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL38 [cytosol] (Gallus gallus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Gallus gallus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Gallus gallus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL38 [cytosol] (Gallus gallus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL38 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:E1BU66

Gene Names

RPL38

Reference Genes

BioGPS Gene:771528 RPL38

ENSEMBL:ENSGALG00000001465

ENSEMBL:ENSGALG00010029495.1 RPL38

KEGG Gene (Gallus gallus):771528 RPL38

Monarch:771528 RPL38

NCBI Gene:771528 RPL38

Reference Transcript

RefSeq:NM_001278012.1 RPL38

Other Identifiers

771528

GO:0003735

GO:0005198

GO:0005829

GO:0005840

GO:0006412

GO:0022618

GO:0022625

GO:0043226

GO:0065003

GO:1990904

GT_A_87_P024485

GT_Xhyb_Chicken_CN217182_568

Gga.6224.1.S1_a_at

Gga.6224.1.S1_s_at

Gga.6224.2.S1_x_at

Participates

as a component of

Inferred From

RPL38 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001264941.1

OpenTargets

ENSG00000172809

Ensembl

ENSGALT00010071305, ENSGALP00010043996, ENSGALG00010029495