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APC [cytosol]
Stable Identifier
R-GGA-5246690
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
K63polyUb-APC, A0A1D5PC88
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Deubiquitination (Gallus gallus)
Ovarian tumor domain proteases (Gallus gallus)
ZRANB1 binds APC (Gallus gallus)
APC [cytosol] (Gallus gallus)
ZRANB1:K63polyUb-APC [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by WNT (Gallus gallus)
Degradation of beta-catenin by the destruction complex (Gallus gallus)
AXIN is phosphorylated in the destruction complex (Gallus gallus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
Association of beta-catenin with the destruction complex (Gallus gallus)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
Beta-catenin phosphorylation cascade (Gallus gallus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Gallus gallus)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Gallus gallus)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Gallus gallus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Gallus gallus)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
Phosphorylation of APC component of the destruction complex (Gallus gallus)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
ZRANB1 binds APC (Gallus gallus)
APC [cytosol] (Gallus gallus)
ZRANB1:K63polyUb-APC [cytosol] (Gallus gallus)
APC [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5PC88
Gene Names
APC
Reference Genes
BioGPS Gene:415607 APC
ENSEMBL:ENSGALG00010008333.1
Monarch:415607 APC
NCBI Gene:415607 APC
UCSC:A0A1D5PC88 APC
Reference Transcript
RefSeq:XM_046905988.1 APC
RefSeq:XM_046935868.1 APC
Other Identifiers
415607
GO:0000281
GO:0000776
GO:0000910
GO:0001708
GO:0005515
GO:0005634
GO:0005737
GO:0005794
GO:0005813
GO:0005815
GO:0005856
GO:0005874
GO:0005881
GO:0005886
GO:0005912
GO:0005923
GO:0006974
GO:0007026
GO:0007094
GO:0007389
GO:0007399
GO:0008013
GO:0008017
GO:0008092
GO:0008285
GO:0008286
GO:0015630
GO:0016055
GO:0016328
GO:0016342
GO:0016477
GO:0019887
GO:0019901
GO:0030027
GO:0030054
GO:0030178
GO:0030335
GO:0030877
GO:0031274
GO:0031625
GO:0032587
GO:0032886
GO:0032991
GO:0043065
GO:0043226
GO:0044877
GO:0045295
GO:0045732
GO:0048471
GO:0048856
GO:0048870
GO:0051010
GO:0051988
GO:0060632
GO:0065003
GO:0070840
GO:0080090
GO:0090090
GO:0120025
GO:1902807
GO:1904781
GO:2000134
GT_A_87_P035507
GT_A_87_P092831
GT_A_87_P115518
Gga.10382.1.S1_s_at
GgaAffx.137.1.S1_at
GgaAffx.25327.1.S1_at
Participates
as an input of
ZRANB1 binds APC (Gallus gallus)
as a component of
ZRANB1:K63polyUb-APC [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
Other forms of this molecule
APC [nucleoplasm]
phospho-APC [cytosol]
APC [cytosol]
APC [cytosol]
APC [cytosol]
Inferred From
K63polyUb-APC [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at unknown position
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
XP_046761944.1
,
XP_046791824.1
ENSEMBL
ENSGALG00010008333
,
ENSGALT00010019940
,
ENSGALP00010011489
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