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chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane]
Stable Identifier
R-GGA-517842
Type
Complex
Species
Gallus gallus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Innate Immune System (Gallus gallus)
Toll-like receptors (TLR) cascades (Gallus gallus)
TLR15 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
TRAF6 binds to p-IRAK2 complexed with activated TLR (Gallus gallus)
chTRAF6 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
p-IRAK2 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
p-IRAK2- TRAF6 dissociates from the activated chTLR complex (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
chTRAF6 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
TLR2 subfamily cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
Activated TLR homo- or heterodimer recruits adaptors TIRAP(or MAL) and MyD88 (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
Autophosphorylation of chicken IRAK4 (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
activated TLR homo- or heterodimer : TIRAP :MyD88 :IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
IRAK2 binds to the IRAK4 accociated with the complex of the activated TLR : TIRAP : MyD88 (Gallus gallus)
IRAK2 : p-IRAK4 :MyD88 : TIRAP : activated TLR [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
IRAK4 recruitment to the activated TLR complexed with ligand, TIRAP and MyD88 (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
activated TLR homo- or heterodimer : TIRAP :MyD88 :IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
TRAF6 binds to p-IRAK2 complexed with activated TLR (Gallus gallus)
chTRAF6 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
p-IRAK2 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
p-IRAK2- TRAF6 dissociates from the activated chTLR complex (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
chTRAF6 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
phosphorylation of IRAK2 by activated IRAK4 (Gallus gallus)
p-IRAK2 : p-IRAK4 : activated TLR : TIRAP : MyD88 [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
IRAK2 : p-IRAK4 :MyD88 : TIRAP : activated TLR [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
TLR2-1 : TLR1-2 heterodimer binds to its ligand (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
TLR4 cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
Activated TLR homo- or heterodimer recruits adaptors TIRAP(or MAL) and MyD88 (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
Autophosphorylation of chicken IRAK4 (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
activated TLR homo- or heterodimer : TIRAP :MyD88 :IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
IRAK2 binds to the IRAK4 accociated with the complex of the activated TLR : TIRAP : MyD88 (Gallus gallus)
IRAK2 : p-IRAK4 :MyD88 : TIRAP : activated TLR [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
IRAK4 recruitment to the activated TLR complexed with ligand, TIRAP and MyD88 (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
activated TLR homo- or heterodimer : TIRAP :MyD88 :IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
TRAF6 binds to p-IRAK2 complexed with activated TLR (Gallus gallus)
chTRAF6 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
p-IRAK2 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
p-IRAK2- TRAF6 dissociates from the activated chTLR complex (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
chTRAF6 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
phosphorylation of IRAK2 by activated IRAK4 (Gallus gallus)
p-IRAK2 : p-IRAK4 : activated TLR : TIRAP : MyD88 [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
IRAK2 : p-IRAK4 :MyD88 : TIRAP : activated TLR [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
TLR5 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
TRAF6 binds to p-IRAK2 complexed with activated TLR (Gallus gallus)
chTRAF6 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
p-IRAK2 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
p-IRAK2- TRAF6 dissociates from the activated chTLR complex (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
chTRAF6 bound to the activated chicken TLR complex [plasma membrane] (Gallus gallus)
ch p-IRAK4 bound to the activated TLR complex [plasma membrane] (Gallus gallus)
activated TLR : TIRAP : MyD88 ; p-IRAK4 [plasma membrane] (Gallus gallus)
activated TLR hetero- or homodimer : TIRAP : MyD88 complex [plasma membrane] (Gallus gallus)
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
chicken TLR2-1 :TLR1-2 bound to its ligand [plasma membrane] (Gallus gallus)
Participants
components
Ligand recognized by chicken TLR2-1 : TLR1-2 heterodimer [plasma membrane]
TLR2-1 : TLR1-2 heteroodimer [plasma membrane]
(Gallus gallus)
Participates
as an output of
TLR2-1 : TLR1-2 heterodimer binds to its ligand (Gallus gallus)
as a member of
activated TLR2 or 4 bound to ligand [plasma membrane] (Gallus gallus)
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