Reactome | MBD3 [nucleoplasm]

MBD3 [nucleoplasm]

Stable Identifier

R-GGA-4657010

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

MBD3, A0A8V1AFX7

Locations in the PathwayBrowser

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Chromatin organization (Gallus gallus)

- ATP-dependent chromatin remodelers (Gallus gallus)
  - CHD chromatin remodelers (Gallus gallus)
    - CHD3, CHD4, CHD5 subfamily (Gallus gallus)
      - NuRD complex assembly (Gallus gallus)
        
        CHD and CDK2AP subunits are recruited to NuRD (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        Interaction of NuRD complexes with transcription factors (Gallus gallus)
        
        GATAD2A NuRD binds ZMYND8:ZNF532:ZNF592:ZNF687 (Gallus gallus)
        
        GATAD2A NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4, RBBP7:MBD2,MBD3:GATAD2A [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        ZMYND8:ZNF532:ZNF592:ZNF687:GATAD2A NuRD [nucleoplasm] (Gallus gallus)
        
        GATAD2A NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4, RBBP7:MBD2,MBD3:GATAD2A [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        NuRD binds Ikaros family member proteins (Gallus gallus)
        
        IKZF1,IKZF2,IKZF3:NuRD [nucleoplasm] (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        NuRD deacetylates telomeric nucleosomes (Gallus gallus)
        
        NR2C2,NR2F2:ZNF827:NuRD:H4K5,H4K8 Ac telomeric chromatin [nucleoplasm] (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        NR2C2,NR2F2:ZNF827:NuRD:telomeric chromatin [nucleoplasm] (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        PHF6 binds NuRD (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        PHF6:NuRD [nucleoplasm] (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        ZNF827 and NR2C2,NR2F2 recruit NuRD to telomeric chromatin (Gallus gallus)
        
        NR2C2,NR2F2:ZNF827:NuRD:H4K5,H4K8 Ac telomeric chromatin [nucleoplasm] (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        NuRD [nucleoplasm] (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD2, MBD3 and GATAD2A, GATAD2B bind core NuRD complex (Gallus gallus)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD2,MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3L2 binds MBD3 NuRD core complex (Gallus gallus)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        MBD3L2:HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Gallus gallus)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)

Gene expression (Transcription) (Gallus gallus)

- RNA Polymerase I Transcription (Gallus gallus)
  - RNA Polymerase I Promoter Clearance (Gallus gallus)
    - RNA Polymerase I Transcription Initiation (Gallus gallus)
      - Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Gallus gallus)
        
        TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
- RNA Polymerase II Transcription (Gallus gallus)
  - Generic Transcription Pathway (Gallus gallus)
    - Transcriptional Regulation by TP53 (Gallus gallus)
      - Regulation of TP53 Activity (Gallus gallus)
        
        Regulation of TP53 Activity through Acetylation (Gallus gallus)
        
        MTA2-NuRD complex deacetylates TP53 (Gallus gallus)
        
        MTA2-NuRD complex [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Intracellular signaling by second messengers (Gallus gallus)
  - PIP3 activates AKT signaling (Gallus gallus)
    - PTEN Regulation (Gallus gallus)
      - Regulation of PTEN gene transcription (Gallus gallus)
        
        SALL4 recruits NuRD to PTEN gene (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)
        
        SALL4:NuRD:PTEN gene [nucleoplasm] (Gallus gallus)
        
        SALL4:NuRD [nucleoplasm] (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        MBD3 [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V1AFX7

Gene Names

MBD3

Reference Genes

ENSEMBL:ENSGALG00010027801.1

UCSC:A0A8V1AFX7 MBD3

Other Identifiers

770153

GO:0000122

GO:0000785

GO:0000792

GO:0003677

GO:0005634

GO:0005654

GO:0005737

GO:0006325

GO:0006338

GO:0006346

GO:0006355

GO:0008327

GO:0009888

GO:0016581

GO:0032991

GO:0048856

GT_A_87_P036979

GT_A_87_P052426

GT_A_87_P235768

GT_Sp_Chicken_CN218608_1533

GgaAffx.11709.1.S1_s_at

Participates

as a component of

as a member of

MBD2,MBD3 [nucleoplasm] (Gallus gallus)

Inferred From

MBD3 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSGALG00010027801, ENSGALT00010067371, ENSGALP00010041212

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