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phospho-MAP2K6 [nucleoplasm]
Stable Identifier
R-GGA-450258
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
p-S207,T211-MAP2K6, A0A1D5PHN6
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular Senescence (Gallus gallus)
Oxidative Stress Induced Senescence (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
Regulation of TP53 Activity (Gallus gallus)
Regulation of TP53 Activity through Acetylation (Gallus gallus)
PI5P Regulates TP53 Acetylation (Gallus gallus)
MAP2K6 phosphorylates PIP4K2B (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-17 signaling (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Innate Immune System (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 10 (TLR10) Cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 2 (TLR2) Cascade (Gallus gallus)
Toll Like Receptor TLR1:TLR2 Cascade (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Toll Like Receptor TLR6:TLR2 Cascade (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 3 (TLR3) Cascade (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 5 (TLR5) Cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Toll Like Receptor 9 (TLR9) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
MAP kinase activation (Gallus gallus)
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
Phosphorylated MKK3/MKK6 migrates to nucleus (Gallus gallus)
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
phospho-MAP2K6 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5PHN6
Gene Names
MAP2K6
Reference Genes
BioGPS Gene:417445 MAP2K6
ENSEMBL:ENSGALG00010029424.1
Monarch:417445 MAP2K6
NCBI Gene:417445 MAP2K6
UCSC:A0A1D5PHN6 MAP2K6
Reference Transcript
RefSeq:XM_004946240.5 MAP2K6
RefSeq:XM_040686493.2 MAP2K6
Other Identifiers
417445
GO:0000165
GO:0000166
GO:0001649
GO:0003012
GO:0003824
GO:0004672
GO:0004674
GO:0004708
GO:0004713
GO:0005524
GO:0005654
GO:0005829
GO:0006468
GO:0006954
GO:0016301
GO:0016740
GO:0019901
GO:0030154
GO:0031098
GO:0038066
GO:0043410
GO:0048856
GO:0051403
GO:0051604
GO:0060048
GO:0060348
GO:0065003
GO:0070269
GO:0071493
GO:0120163
GO:0140096
GO:1902531
GO:1904784
GT_A_87_P017548
Gga.13002.1.S1_at
GgaAffx.26190.1.S1_at
Participates
as a member of
p-S189,T193-MAP2K3, p-S207,T211-MAP2K6 [nucleoplasm] (Gallus gallus)
Other forms of this molecule
MAP2K6 [cytosol]
phospho-MAP2K6 [cytosol]
Inferred From
p-S207,T211-MAP2K6 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 207 (in Homo sapiens)
Coordinate
207
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 211 (in Homo sapiens)
Coordinate
211
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
XP_040542427.1
,
XP_004946297.1
ENSEMBL
ENSGALG00010029424
,
ENSGALT00010071187
,
ENSGALP00010043878
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