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IL6ST [plasma membrane]
Stable Identifier
R-GGA-448453
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
IL6ST, A0A8V0YBA0
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Gallus gallus)
Cell junction organization (Gallus gallus)
Cell-cell junction organization (Gallus gallus)
Adherens junctions interactions (Gallus gallus)
Activation of STAT3 by cadherin engagement (Gallus gallus)
Assembly of hexameric IL-6 receptor (Gallus gallus)
IL6 receptor hexamer:JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6ST is tyrosine phosphorylated (Gallus gallus)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
JAK activation (Gallus gallus)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6 receptor hexamer:JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-12 family signaling (Gallus gallus)
Interleukin-35 Signalling (Gallus gallus)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Gallus gallus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Gallus gallus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Gallus gallus)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL35:(IL6ST:p-JAK1:p-JAK2:p-TYK2) dimer [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1:p-JAK2:p-TYK2 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Gallus gallus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
STAT1 associates with IL6ST:IL6ST (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
p-STAT1 dissociates from IL6ST:IL6ST (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
Interleukin-6 family signaling (Gallus gallus)
IL-6-type cytokine receptor ligand interactions (Gallus gallus)
LIFR:JAKs bind gp130:JAKs:CNTFR (Gallus gallus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:gp130:JAKs:LIFR:JAKs [plasma membrane] (Gallus gallus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
OSM,LIF,CTF1 receptor complex binds gp130 (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
LIF,OSM receptor complex:gp130 [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
gp130:JAKs bind CNTFR (Gallus gallus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
Interleukin-6 signaling (Gallus gallus)
Assembly of hexameric IL-6 receptor (Gallus gallus)
IL6 receptor hexamer:JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6ST is tyrosine phosphorylated (Gallus gallus)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
JAK activation (Gallus gallus)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6 receptor hexamer:JAKs [plasma membrane] (Gallus gallus)
IL6 receptor trimer:JAKs [plasma membrane] (Gallus gallus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6ST [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0YBA0
Gene Names
IL6ST
Reference Genes
ENSEMBL:ENSGALG00010012930.1
UCSC:A0A8V0YBA0 IL6ST
Other Identifiers
395684
GO:0002821
GO:0004896
GO:0004897
GO:0004915
GO:0004921
GO:0004923
GO:0004924
GO:0005127
GO:0005138
GO:0005515
GO:0005886
GO:0005896
GO:0005900
GO:0005977
GO:0007165
GO:0007259
GO:0008284
GO:0008593
GO:0009897
GO:0015026
GO:0016020
GO:0019221
GO:0019838
GO:0019955
GO:0019970
GO:0019981
GO:0030154
GO:0030296
GO:0030425
GO:0034097
GO:0038154
GO:0038165
GO:0042102
GO:0042802
GO:0043025
GO:0043235
GO:0043524
GO:0044297
GO:0045121
GO:0045509
GO:0045669
GO:0045747
GO:0048711
GO:0048856
GO:0048861
GO:0060576
GO:0070102
GO:0070106
GO:0070110
GO:0070120
GO:0097110
GO:0097696
GO:0098772
GT_A_87_P015927
GT_A_87_P037522
Gga.2225.1.S1_at
Gga.7731.1.S1_at
Participates
as a component of
IL6ST:p-JAK1:p-JAK2:p-TYK2 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL6ST:p-JAK1 [plasma membrane] (Gallus gallus)
LIF,OSM receptor complex:gp130 [plasma membrane] (Gallus gallus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Gallus gallus)
IL6RB:Activated JAKs [plasma membrane] (Gallus gallus)
as an input of
OSM,LIF,CTF1 receptor complex binds gp130 (Gallus gallus)
Other forms of this molecule
IL6ST [extracellular region]
phospho-IL6ST [plasma membrane]
Inferred From
IL6ST [plasma membrane]
(Homo sapiens)
Cross References
ENSEMBL
ENSGALT00010031044
,
ENSGALG00010012930
,
ENSGALP00010018047
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