Reactome | ACTA2 [cytosol]

ACTA2 [cytosol]

Stable Identifier

R-GGA-445792

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

ACTA2, A0A8V0ZG93

Locations in the PathwayBrowser

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Cell-Cell communication (Gallus gallus)

- Cell junction organization (Gallus gallus)
  - Cell-cell junction organization (Gallus gallus)
    - Adherens junctions interactions (Gallus gallus)
      - Activation of STAT3 by cadherin engagement (Gallus gallus)
        
        CDH1 forms homotypic trans-dimers (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Gallus gallus)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        trans-homotypic CDH1 cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        CDH1-associated CTNNA1 binds F-actin (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        CDH1-associated CTNNA1 binds VCL (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        Cell-to-cell contact through homophilic cadherin interactions inhibits RAC1/CDC42 ubiquitination (Gallus gallus)
        
        Engaged CDH1,(CDH11) [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Gallus gallus)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
      - Regulation of Homotypic Cell-Cell Adhesion (Gallus gallus)
        
        Regulation of Expression and Function of Type I Classical Cadherins (Gallus gallus)
        
        Regulation of CDH1 Expression and Function (Gallus gallus)
        
        Regulation of CDH1 Function (Gallus gallus)
        
        CDH1 forms homotypic trans-dimers (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Gallus gallus)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        trans-homotypic CDH1 cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        CDH1-associated CTNNA1 binds F-actin (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        CDH1-associated CTNNA1 binds VCL (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)

Muscle contraction (Gallus gallus)

- Smooth Muscle Contraction (Gallus gallus)
  - ATP Hydrolysis By Myosin (Gallus gallus)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
      - F-actin (ACTA2,ACTG2:ATP) [cytosol] (Gallus gallus)
        
        (ACTA2,ACTG2):ATP [cytosol] (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
      - F-actin (ACTA2,ACTG2:ATP) [cytosol] (Gallus gallus)
        
        (ACTA2,ACTG2):ATP [cytosol] (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
  - Calcium Binds Caldesmon (Gallus gallus)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
      - F-actin (ACTA2,ACTG2:ATP) [cytosol] (Gallus gallus)
        
        (ACTA2,ACTG2):ATP [cytosol] (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
    - Inactive Myosin Actin Contractile Complex [plasma membrane] (Gallus gallus)
      - F-actin (ACTA2,ACTG2:ATP) [cytosol] (Gallus gallus)
        
        (ACTA2,ACTG2):ATP [cytosol] (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
  - Myosin Binds ATP (Gallus gallus)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
      - F-actin (ACTA2,ACTG2:ATP) [cytosol] (Gallus gallus)
        
        (ACTA2,ACTG2):ATP [cytosol] (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
    - p-S CALD1-Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
      - F-actin (ACTA2,ACTG2:ATP) [cytosol] (Gallus gallus)
        
        (ACTA2,ACTG2):ATP [cytosol] (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
  - Release Of ADP From Myosin (Gallus gallus)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
      - F-actin (ACTA2,ACTG2:ATP) [cytosol] (Gallus gallus)
        
        (ACTA2,ACTG2):ATP [cytosol] (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
      - F-actin (ACTA2,ACTG2:ATP) [cytosol] (Gallus gallus)
        
        (ACTA2,ACTG2):ATP [cytosol] (Gallus gallus)
        
        ACTA2, ACTG2 [cytosol] (Gallus gallus)
        
        ACTA2 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0ZG93

Gene Names

ACTA2

Reference Genes

ENSEMBL:ENSGALG00010022071.1

UCSC:A0A8V0ZG93 ACTA2

Other Identifiers

423787

GO:0000166

GO:0003012

GO:0003013

GO:0005524

GO:0005737

GO:0005856

GO:0005929

GO:0008217

GO:0009615

GO:0014829

GO:0015629

GO:0019901

GO:0030485

GO:0031514

GO:0032982

GO:0032991

GO:0043226

GO:0048856

GO:0072144

GT_A_87_P014692

GT_A_87_P202303

GT_Xhyb_Chicken_CO759428_3895

Gga.4530.1.S1_at

Participates

as a member of

ACTA2, ACTG2 [cytosol] (Gallus gallus)

Inferred From

ACTA2 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSGALT00010053678, ENSGALP00010032331, ENSGALG00010022071

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