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NUMB [plasma membrane]
Stable Identifier
R-GGA-443595
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
NUMB, A0A8V0ZGI6
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
L1CAM interactions (Gallus gallus)
Recycling pathway of L1 (Gallus gallus)
Interaction of NUMB with L1 (Gallus gallus)
CRMP-2:NUMB:alpha adaptin [plasma membrane] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
L1:NUMB:CRMP-2:alpha-adaptin [clathrin-coated endocytic vesicle] (Gallus gallus)
CRMP-2:NUMB:alpha adaptin [plasma membrane] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Hedgehog (Gallus gallus)
Hedgehog 'off' state (Gallus gallus)
Degradation of GLI1 by the proteasome (Gallus gallus)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB:ITCH:ub-pS-GLI1:SUFU [cytosol] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB binds ITCH (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB:ITCH bind and ubiquitnate GLI1 (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB:ITCH:ub-pS-GLI1:SUFU [cytosol] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
Hedgehog 'on' state (Gallus gallus)
NUMB binds ITCH (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB:ITCH binds GLI1 (Gallus gallus)
GLI1:NUMB:ITCH [cytosol] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
NUMB:ITCH ubiquitinates GLI1 (Gallus gallus)
GLI1:NUMB:ITCH [cytosol] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
ub-GLI1:NUMB:ITCH [cytosol] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
ub-GLI is degraded by the proteasome (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
ub-GLI1:NUMB:ITCH [cytosol] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
NUMB [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0ZGI6
Gene Names
NUMB
Reference Genes
ENSEMBL:ENSGALG00010020945.1
UCSC:A0A8V0ZGI6 NUMB
Other Identifiers
395639
GO:0005737
GO:0005768
GO:0005769
GO:0005886
GO:0005905
GO:0007399
GO:0007405
GO:0007409
GO:0008013
GO:0016020
GO:0016323
GO:0021670
GO:0021849
GO:0030136
GO:0030335
GO:0030900
GO:0031410
GO:0034330
GO:0034332
GO:0045177
GO:0045294
GO:0045296
GO:0048856
GO:0050769
GO:0098978
GO:0099149
GO:1903077
GT_A_87_P011752
GT_A_87_P084881
GT_A_87_P084886
Gga.266.1.S1_s_at
Gga.4410.1.S1_s_at
GgaAffx.5862.1.S1_at
GgaAffx.5862.1.S1_s_at
Participates
as a component of
CRMP-2:NUMB:alpha adaptin [plasma membrane] (Gallus gallus)
NUMB:ITCH [cytosol] (Gallus gallus)
as an input of
NUMB binds ITCH (Gallus gallus)
Inferred From
NUMB [plasma membrane]
(Homo sapiens)
Cross References
ENSEMBL
ENSGALT00010050632
,
ENSGALG00010020945
,
ENSGALP00010029891
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