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viral dsRNA : TLR3 : TICAM1 : pUb_TRAF6 :TAB2 :TAB3: TAK1 : TAB1: free_pUb_chain [endosome membrane]
Stable Identifier
R-GGA-434146
Type
Complex
Species
Gallus gallus
Related Species
Infectious bronchitis virus
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Innate Immune System (Gallus gallus)
Toll-like receptors (TLR) cascades (Gallus gallus)
TLR3 cascade (Gallus gallus)
TRAF6 mediated induction of proinflammatory cytokines (Gallus gallus)
Activation of recruited TAK1 (Gallus gallus)
viral dsRNA : TLR3 : TICAM1 : pUb_TRAF6 :TAB2 :TAB3: TAK1 : TAB1: free_pUb_chain [endosome membrane] (Gallus gallus)
TRAF6 recruits TAK1 kinase complex (Gallus gallus)
viral dsRNA : TLR3 : TICAM1 : pUb_TRAF6 :TAB2 :TAB3: TAK1 : TAB1: free_pUb_chain [endosome membrane] (Gallus gallus)
Participants
components
x 2
free K63_polyubiquitin chain [cytosol]
(Gallus gallus)
x 2
TAK1 : TAB1 : TAB2/TAB3 complex [endosome membrane]
(Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane]
(Gallus gallus)
Participates
as an output of
TRAF6 recruits TAK1 kinase complex (Gallus gallus)
as an input of
Activation of recruited TAK1 (Gallus gallus)
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