Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TBK1 [cytosol]
Stable Identifier
R-GGA-434016
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Innate Immune System (Gallus gallus)
RLR (RIG-like receptor) mediated induction of IFN alpha/beta (Gallus gallus)
TRAF mediated activation of IRF (Gallus gallus)
TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation (Gallus gallus)
TBK1/IKK epsilon : SIKE-1 [cytosol] (Gallus gallus)
TBK1/IKK epsilon [cytosol] (Gallus gallus)
TBK1 [cytosol] (Gallus gallus)
Toll-like receptors (TLR) cascades (Gallus gallus)
TLR3 cascade (Gallus gallus)
IKK related kinases bound to dsRNA:TLR3:TICAM1 activate IRF3 (Gallus gallus)
Viral dsRNA:TLR3:TICAM1 Complex Activates TBK1 (Gallus gallus)
Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 (Gallus gallus)
TBK1 [cytosol] (Gallus gallus)
TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex (Gallus gallus)
TBK1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
ENSEMBL:ENSGALP00000015982 TBK1
Gene Names
TBK1
Participates
as a member of
TBK1/IKK epsilon [cytosol] (Gallus gallus)
as an input of
TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex (Gallus gallus)
Other forms of this molecule
phospho-TBK1 [mitochondrial outer membrane]
TBK1 [endosome membrane]
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text