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TRAF6 [endosome membrane]
Stable Identifier
R-GGA-433792
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
endosome membrane
Locations in the PathwayBrowser
for Species:
Homo sapiens
Gallus gallus
Expand all
Innate Immune System (Gallus gallus)
Toll-like receptors (TLR) cascades (Gallus gallus)
TLR21 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
Activated TAK1 leaves endosome membrane (Gallus gallus)
p-IRAK2: pUb_oligo TRAF6 : phospho TAK1 :TAB1 : TAB2/TAB3 : K63linked free pUb chain [cytosol] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
p-IRAK2: pUb_oligo TRAF6 : phospho TAK1 :TAB1 : TAB2/TAB3 : K63linked free pUb chain [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
p-IRAK2:oligo pUb TRAF6 : TAK1 :TAB1 : TAB2/TAB3 : free K63 pUb chains [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Activated TRAF6 synthesizes free K63 linked pUb chains (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation (Gallus gallus)
p-IRAK2: pUb_oligo TRAF6 : phospho TAK1 :TAB1 : TAB2/TAB3 : K63linked free pUb chain [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
p-IRAK2:oligo pUb TRAF6 : TAK1 :TAB1 : TAB2/TAB3 : free K63 pUb chains [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Autoubiquitination of oligoTRAF6 bound to p-IRAK2 (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
oligo TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 binding to IRAK2 stimulates its oligomerizartion upon TLR7 or TLR21 stimulation (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6:p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
oligo TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 (Gallus gallus)
TRAF6 bound to activated TLR7 or 21 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 (Gallus gallus)
TRAF6 bound to activated TLR7 or 21 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6:p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TLR3 cascade (Gallus gallus)
TRAF6 mediated induction of proinflammatory cytokines (Gallus gallus)
Activated chicken TAK1 dissociates from the activated TLR3 complex (Gallus gallus)
viral dsRNA : TLR3 : TICAM1 : pUb_TRAF6 :TAB2:TAB3 :phospho TAK1 : TAB1 : free pUb chain [endosome membrane] (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Activated chicken TRAF6 synthesizes free K63bound poly_Ub chains within the complex dsRNA :TLR3 :TICAM1 (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Activation of recruited TAK1 (Gallus gallus)
viral dsRNA : TLR3 : TICAM1 : pUb_TRAF6 :TAB2 :TAB3: TAK1 : TAB1: free_pUb_chain [endosome membrane] (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
viral dsRNA : TLR3 : TICAM1 : pUb_TRAF6 :TAB2:TAB3 :phospho TAK1 : TAB1 : free pUb chain [endosome membrane] (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6 (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 recruits TAK1 kinase complex (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
viral dsRNA : TLR3 : TICAM1 : pUb_TRAF6 :TAB2 :TAB3: TAK1 : TAB1: free_pUb_chain [endosome membrane] (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
viral dsRNA: TLR3: TICAM1 recruits TRAF6 (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TLR7 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
Activated TAK1 leaves endosome membrane (Gallus gallus)
p-IRAK2: pUb_oligo TRAF6 : phospho TAK1 :TAB1 : TAB2/TAB3 : K63linked free pUb chain [cytosol] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
p-IRAK2: pUb_oligo TRAF6 : phospho TAK1 :TAB1 : TAB2/TAB3 : K63linked free pUb chain [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
p-IRAK2:oligo pUb TRAF6 : TAK1 :TAB1 : TAB2/TAB3 : free K63 pUb chains [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Activated TRAF6 synthesizes free K63 linked pUb chains (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation (Gallus gallus)
p-IRAK2: pUb_oligo TRAF6 : phospho TAK1 :TAB1 : TAB2/TAB3 : K63linked free pUb chain [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
p-IRAK2:oligo pUb TRAF6 : TAK1 :TAB1 : TAB2/TAB3 : free K63 pUb chains [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Autoubiquitination of oligoTRAF6 bound to p-IRAK2 (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
oligo TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
oligo pUb-TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 binding to IRAK2 stimulates its oligomerizartion upon TLR7 or TLR21 stimulation (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6:p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
oligo TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 (Gallus gallus)
TRAF6 bound to activated TLR7 or 21 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 (Gallus gallus)
TRAF6 bound to activated TLR7 or 21 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
TRAF6:p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 [endosome membrane] (Gallus gallus)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
TICAM1,TRAF6-dependent induction of TAK1 complex (Homo sapiens)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation (Homo sapiens)
TRAF6 [endosome membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1C626 TRAF6
Gene Names
TRAF6
Reference Genes
BioGPS Gene:423163 TRAF6
KEGG:gga:423163 TRAF6
Monarch:423163 TRAF6
NCBI Gene:423163 TRAF6
UCSC:E1C626 TRAF6
Reference Transcript
RefSeq:XM_046942059.1 TRAF6
RefSeq:XM_004941546.5 TRAF6
RefSeq:XM_004941548.5 TRAF6
RefSeq:XM_015287208.4 TRAF6
RefSeq:XM_046942060.1 TRAF6
RefSeq:XM_004941545.5 TRAF6
RefSeq:XM_004941547.5 TRAF6
Other Identifiers
423163
GO:0000045
GO:0000122
GO:0000209
GO:0001503
GO:0001843
GO:0002224
GO:0002376
GO:0002637
GO:0002726
GO:0002753
GO:0002755
GO:0003824
GO:0004842
GO:0005164
GO:0005515
GO:0005634
GO:0005737
GO:0005811
GO:0005829
GO:0005886
GO:0005938
GO:0006351
GO:0006355
GO:0006955
GO:0006974
GO:0007165
GO:0007249
GO:0008270
GO:0009299
GO:0009887
GO:0009898
GO:0016071
GO:0016567
GO:0016740
GO:0019886
GO:0023035
GO:0030154
GO:0030316
GO:0030674
GO:0031624
GO:0031663
GO:0031666
GO:0032481
GO:0032735
GO:0032743
GO:0032755
GO:0032991
GO:0033209
GO:0034142
GO:0034450
GO:0035591
GO:0035631
GO:0038061
GO:0038172
GO:0038173
GO:0042088
GO:0042102
GO:0042742
GO:0042802
GO:0042826
GO:0042981
GO:0043011
GO:0043122
GO:0043123
GO:0043124
GO:0043226
GO:0043422
GO:0045087
GO:0045453
GO:0045672
GO:0045892
GO:0045944
GO:0046330
GO:0046849
GO:0046872
GO:0048468
GO:0048471
GO:0048856
GO:0050852
GO:0051865
GO:0060090
GO:0061630
GO:0070498
GO:0070534
GO:0070555
GO:0070936
GO:0071222
GO:0071345
GO:0097400
GO:0098542
GO:0098696
GO:0098978
GO:0140096
GO:0140374
GO:0141124
GO:0141198
GO:1901701
GO:1904996
GT_A_87_P018386
GT_A_87_P084486
Gga.14428.1.S1_at
GgaAffx.4973.1.S1_at
GgaAffx.4973.2.S1_s_at
Participates
as an input of
TRAF6 binding to IRAK2 stimulates its oligomerizartion upon TLR7 or TLR21 stimulation (Gallus gallus)
as a component of
oligo TRAF6 : p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6:p-IRAK2 [endosome membrane] (Gallus gallus)
TRAF6 bound to activated TLR7 or 21 [endosome membrane] (Gallus gallus)
viral ds RNA : TLR3 : TICAM1 : TRAF6 [endosome membrane] (Gallus gallus)
pUb_TRAF6 [endosome membrane] (Gallus gallus)
Other forms of this molecule
TRAF6 [cytosol]
TRAF6 [cytosol]
TRAF6 [mitochondrial outer membrane]
K63-Ub-TRAF6 [mitochondrial outer membrane]
TRAF6 [plasma membrane]
K63-linked Ub TRAF6 [plasma membrane]
TRAF6 [cytosol]
TRAF6 [endosome membrane]
TRAF6 [endosome membrane]
TRAF6 [plasma membrane]
TRAF6 [plasma membrane]
TRAF6 [cytosol]
TRAF6 [cytosol]
Cross References
RefSeq
XP_046798015.1
,
XP_004941604.1
,
XP_015142694.1
,
XP_004941605.1
,
XP_004941602.1
,
XP_004941603.1
,
XP_046798016.1
ENSEMBL
ENSGALP00010037979
,
ENSGALT00010061479
,
ENSGALG00010025204
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