orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2

Stable Identifier
R-GGA-419461
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
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orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2
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The orotidine 5'-phosphate decarboxylase activity of dimeric UMPS (uridine monophosphate synthetase) catalyzes the reaction of orotidine 5'-monophosphate (OMP) to form uridine 5'-monophosphate (UMP) and CO2. The chicken enzyme is known only as the product of a large-scale sequencing project to identify chicken mRNAs; all molecular details of the reaction are inferred from its human counterpart.
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Catalyst Activity

orotidine-5'-phosphate decarboxylase activity of UMPS dimer [cytosol]

Physical Entity
UMPS dimer [cytosol] (Gallus gallus)
Activity
orotidine-5'-phosphate decarboxylase activity (GO:0004590)
Inferred From
UMPS dimer decarboxylates OMP to UMP (Homo sapiens)
Authored
D'Eustachio, P  (2009-05-01)
Created
D'Eustachio, P  (2009-05-01)
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