Reactome | CENPI [cytosol]

CENPI [cytosol]

Stable Identifier

R-GGA-375293

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

CENPI, A0A8V0YN82

Locations in the PathwayBrowser

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Cell Cycle (Gallus gallus)

- Cell Cycle Checkpoints (Gallus gallus)
  - Mitotic Spindle Checkpoint (Gallus gallus)
    - Amplification of signal from the kinetochores (Gallus gallus)
      - Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Gallus gallus)
        
        MAD2 associates with the Mad1 kinetochore complex (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        MAD2 converted to an inhibitory state via interaction with Mad1 (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Mad1 binds kinetochore (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Release of activated MAD2 from kinetochores (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
- Cell Cycle, Mitotic (Gallus gallus)
  - M Phase (Gallus gallus)
    - Mitotic Metaphase and Anaphase (Gallus gallus)
      - Mitotic Anaphase (Gallus gallus)
        
        Separation of Sister Chromatids (Gallus gallus)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Gallus gallus)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
    - Mitotic Prometaphase (Gallus gallus)
      - EML4 and NUDC in mitotic spindle formation (Gallus gallus)
        
        EML4 recruits NUDC to mitotic spindle (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
      - Resolution of Sister Chromatid Cohesion (Gallus gallus)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Gallus gallus)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Kinetochore assembly (Gallus gallus)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Gallus gallus)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Gallus gallus)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
  - Signaling by Rho GTPases (Gallus gallus)
    - RHO GTPase Effectors (Gallus gallus)
      - RHO GTPases Activate Formins (Gallus gallus)
        
        AURKB phosphorylates DIAPH2-2 at kinetochores (Gallus gallus)
        
        Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        CDC42:GTP recruits DIAPH2-2 to kinetochores (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)
        
        Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        CCAN network [cytosol] (Gallus gallus)
        
        CENP-(H,I, K) complex [cytosol] (Gallus gallus)
        
        CENPI [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0YN82

Gene Names

CENPI

Reference Genes

BioGPS Gene:395207 CENPI

ENSEMBL:ENSGALG00010016129.1

KEGG:gga:395207 CENPI

Monarch:395207 CENPI

NCBI Gene:395207 CENPI

UCSC:A0A8V0YN82 CENPI

Reference Transcript

Other Identifiers

395207

GO:0000070

GO:0000775

GO:0000776

GO:0000939

GO:0005634

GO:0005654

GO:0005694

GO:0006325

GO:0016604

GO:0034080

GO:0034508

GO:0043226

GO:0065003

GT_A_87_P038125

GT_A_87_P120573

Gga.31.1.S1_at

Participates

as a component of

CENP-(H,I, K) complex [cytosol] (Gallus gallus)

Other forms of this molecule

CENPI [nucleoplasm]

Inferred From

CENPI [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_046795817.1, XP_046795818.1, NP_989863.2

ENSEMBL

ENSGALP00010022448, ENSGALG00010016129, ENSGALT00010038829

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