Reactome | CCL4 [extracellular region]

CCL4 [extracellular region]

Stable Identifier

R-GGA-373108-4

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

extracellular region

Synonyms

CCL5(24-91), Q90826

Locations in the PathwayBrowser

Expand all

Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (i) signalling events (Gallus gallus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Gallus gallus)
        
        Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)
        
        CCL4 [extracellular region] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Gallus gallus)
        
        Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)
        
        CCL4 [extracellular region] (Gallus gallus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Gallus gallus)
        
        Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)
        
        CCL4 [extracellular region] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Gallus gallus)
        
        Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)
        
        CCL4 [extracellular region] (Gallus gallus)
      - The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Gallus gallus)
        
        Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)
        
        CCL4 [extracellular region] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Gallus gallus)
        
        Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)
        
        CCL4 [extracellular region] (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
      - Peptide ligand-binding receptors (Gallus gallus)
        
        Chemokine receptors bind chemokines (Gallus gallus)
        
        Receptors CCR3, 4 and 5 bind CCL5 ligand (Gallus gallus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Gallus gallus)
        
        Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)
        
        CCL4 [extracellular region] (Gallus gallus)
        
        Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)
        
        CCL4 [extracellular region] (Gallus gallus)

External Reference Information

External Reference

UniProt:Q90826

Gene Names

CCL4

Reference Genes

BioGPS Gene:395551 CCL4

ENSEMBL:ENSGALG00010029562

KEGG:gga:395551 CCL4

Monarch:395551 CCL4

NCBI Gene:395551 CCL4

UCSC:Q90826 CCL4

Other Identifiers

395551

GO:0002376

GO:0005125

GO:0005576

GO:0005615

GO:0006935

GO:0006954

GO:0006955

GO:0008009

GO:0030335

GO:0048018

GO:0048020

GO:0048245

GO:0048870

GO:0061844

GO:0070098

GO:0098542

GO:0098772

GT_A_87_P066056

GT_A_87_P066066

Gga.4409.1.S1_a_at

Participates

as a member of

Homologues of CCL5(24-91) [extracellular region] (Gallus gallus)

Other forms of this molecule

CCL4 [extracellular region]

Inferred From

CCL5(24-91) [extracellular region] (Homo sapiens)

Cross References

ENSEMBL

ENSGALT00010071450, ENSGALP00010044140, ENSGALG00010029562

PRO

Q90826