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apoTF [extracellular region]
Stable Identifier
R-GGA-350754
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
extracellular region
Synonyms
A0A8V0ZZF1
Locations in the PathwayBrowser
Expand all
Hemostasis (Gallus gallus)
Platelet activation, signaling and aggregation (Gallus gallus)
Response to elevated platelet cytosolic Ca2+ (Gallus gallus)
Platelet degranulation (Gallus gallus)
Release of platelet secretory granule components (Gallus gallus)
Platelet releasate secretory granule proteins [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
Transport of small molecules (Gallus gallus)
Iron uptake and transport (Gallus gallus)
Transferrin endocytosis and recycling (Gallus gallus)
TFRC dimer binds 2xholoTF (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
apo-Transferrin dissociates from the receptor complex (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
apoTF:TFRC dimer [plasma membrane] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
apoTF:TFRC dimer translocates from endosome membrane to plasma membrane (Gallus gallus)
apoTF:TFRC dimer [plasma membrane] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
apoTF binds 2Fe3+ to form holoTF (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
Vesicle-mediated transport (Gallus gallus)
Membrane Trafficking (Gallus gallus)
Clathrin-mediated endocytosis (Gallus gallus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
Cargo recognition for clathrin-mediated endocytosis (Gallus gallus)
AP-2 directly binds some endocytic cargo (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
Clathrin recruits PIK3C2A (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
SNX9 recruits components of the actin polymerizing machinery (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
apoTF [extracellular region] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0ZZF1
Reference Genes
ENSEMBL:ENSGALG00010024717.1
UCSC:A0A8V0ZZF1
Other Identifiers
396241
GO:0001530
GO:0001817
GO:0002227
GO:0002376
GO:0004869
GO:0005506
GO:0005576
GO:0005615
GO:0005737
GO:0005768
GO:0005769
GO:0005886
GO:0006811
GO:0006826
GO:0008201
GO:0008289
GO:0009986
GO:0019731
GO:0019732
GO:0030141
GO:0031640
GO:0031665
GO:0032680
GO:0032991
GO:0033690
GO:0034145
GO:0042581
GO:0043123
GO:0043539
GO:0044793
GO:0045071
GO:0045669
GO:0046872
GO:0048525
GO:0050829
GO:0055037
GO:0060349
GO:0061844
GO:0098542
GO:0098772
GO:0140912
GO:1900229
GO:1902732
GT_A_87_P245653
GT_A_87_P252428
GT_A_87_P265293
GT_A_87_P300658
GT_Xhyb_Chicken_BG641495_143
GT_Xhyb_Chicken_BG641709_206
GT_Xhyb_Chicken_BG641950_266
GT_Xhyb_Chicken_BG641977_271
GT_Xhyb_Chicken_CN219993_1608
GT_Xhyb_Chicken_CN225724_3290
Gga.2551.2.S1_a_at
Gga.2551.2.S1_s_at
Participates
as a member of
Platelet releasate secretory granule proteins [extracellular region] (Gallus gallus)
as an output of
apo-Transferrin dissociates from the receptor complex (Gallus gallus)
as an input of
apoTF binds 2Fe3+ to form holoTF (Gallus gallus)
as a component of
apoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF [extracellular region] (Gallus gallus)
Other forms of this molecule
apoTF [clathrin-coated endocytic vesicle membrane]
TF [secretory granule lumen]
LTF [specific granule lumen]
LTF [tertiary granule lumen]
LTF [phagocytic vesicle lumen]
LTF [extracellular region]
phospho-p-TF [endoplasmic reticulum lumen]
TF [endoplasmic reticulum lumen]
apoTF [endosome membrane]
Inferred From
apoTF [extracellular region]
(Homo sapiens)
Cross References
ENSEMBL
ENSGALP00010037098
,
ENSGALG00010024717
,
ENSGALT00010060339
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